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https://pubmed.ncbi.nlm.nih.gov/25415508/
The extracellular matrix (ECM) is a highly dynamic structure that is present in all tissues and continuously undergoes controlled remodelling. This process involves quantitative and qualitative changes in the ECM, mediated by specific enzymes that are responsible for ECM degradation, such as metallo …Cited by: 2414
https://pubmed.ncbi.nlm.nih.gov/32992998/
With advancing age, the skeletal muscle extracellular matrix (ECM) undergoes fibrotic changes that may lead to increased muscle stiffness, injury susceptibility and strength loss. This study tested the potential of different exercises to counter these changes by stimulating the activity of genes associated with ECM remodeling.Cited by: 2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225943/
The extracellular matrix (ECM) serves diverse functions and is a major component of the cellular microenvironment. The ECM is a highly dynamic structure, constantly undergoing a remodeling process where ECM components are deposited, degraded, or otherwise modified.Cited by: 1543
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.14-266668
Mar 25, 2015 · This study determined the contribution of extracellular matrix (ECM) remodeling to the protective adaptation of human skeletal muscle known as the repeated-bout effect (RBE). Muscle biopsies were obtained 3 hours, 2 days, and 27 days following an initial bout (B1) of lengthening contractions (LCs) and 2 days following a repeated bout (B2) in 2 separate studies.Cited by: 90
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815558/
ECM Proteins Involved in LV Remodeling. It is estimated that approximately 140 different protein components make up the ECM , and several ECM components are known to be involved in post-MI LV remodeling. ECM proteins include those that provide structure (e.g., collagens, fibronectin, and laminin) as well as those that provide support roles.Cited by: 21
https://link.springer.com/referenceworkentry/10.1007/978-3-642-16483-5_2068
Mar 10, 2017 · ECM is produced and assembled by the cells it is surrounding. The main components of ECM include glycosaminoglycans (with predominant hyaluronic acid) and proteoaminoglycans (e.g., perlecan, aggrecan), noncolagenous glycoproteins (such as fibronectin, laminins, and tenascin), collagens, and many other biologically important molecules involved in cell–cell and cell–matrix …
https://www.sciencedirect.com/science/article/pii/S0092867420306838
Jul 23, 2020 · Neuronal IL-33 induces microglial remodeling of the extracellular matrix. ... Brains were post-fixed in 4% PFA for a minimum of 4 hours and then transferred to a 30% sucrose solution for a minimum of 2 days. Brains were then flash frozen and sliced in 40 um thick coronal sections on a HM 440E freezing microtome (GMI Instruments). ...
https://www.ahajournals.org/doi/10.1161/01.CIR.101.25.2981
Jun 27, 2000 · Postinfarction remodeling has been arbitrarily divided into an early phase (within 72 hours) and a late phase (beyond 72 hours). The early phase involves expansion of the infarct zone, 5 which may result in early ventricular rupture or aneurysm formation. Late remodeling involves the left ventricle globally and is associated with time-dependent dilatation, the distortion of ventricular shape, …
https://www.liebertpub.com/doi/10.1089/ten.TEB.2021.0066
Jun 03, 2021 · This reciprocal cell-ECM interaction is crucial for the conservation of cell and tissue functions and homeostasis. In vitro ECM remodeling also plays a key role in regulating the lineage fate of SCs. A deeper understanding of in vitro ECM remodeling may provide new perspectives for the maintenance of SC function.Author: Yuan-Hao Xie, Chen-Qi Tang, Zi-Zhan Huang, Si-Cheng Zhou, Yu-Wei Yang, Zi Yin, Boon Chin Heng, Wei-S...
https://www.nature.com/articles/srep39498
Jan 03, 2017 · Invasive cancer cells interact with the surrounding extracellular matrix (ECM), remodeling ECM fiber network structure by condensing, degrading, and aligning these fibers. ... and 21 hours post ...
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