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https://www.sciencedirect.com/science/article/pii/S0006291X0702637X
Epidermal growth factor (EGF) receptor targeted delivery of PEGylated adenovirus. Abstract. A biotin–polyethylene glycol (PEG)–epidermal growth factor (EGF) conjugate was immobilized onto the surface of avidin-modified adenovirus (ADV-Avi) via biotin–avidin interaction to deliver ADV specifically to EGF receptor over-expressing cancer cells.Author: Ji Won Park, Hyejung Mok, Tae Gwan Park
https://www.researchgate.net/publication/5765828_Epidermal_growth_factor_EGF_receptor_targeted_delivery_of_PEGylated_adenovirus
A biotin-polyethylene glycol (PEG)-epidermal growth factor (EGF) conjugate was immobilized onto the surface of avidin-modified adenovirus (ADV-Avi) via biotin-avidin interaction to deliver ADV ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070097/
Induction of iodide accumulation after systemic EGFR-targeted NIS gene transfer in vivo. To investigate the iodide uptake activity in HuH7 tumors after systemic in vivo NIS gene transfer, 123I distribution was monitored in tumor-bearing mice 24 hours after administration of polyplexes (Figure 2).Author: Kathrin Klutz, David Schaffert, Michael J Willhauck, Geoffrey K Grünwald, Rudolf Haase, Nathalie Wun...
https://www.deepdyve.com/lp/elsevier/epidermal-growth-factor-egf-receptor-targeted-delivery-of-pegylated-DGLpXklkMz
Feb 15, 2008 · A biotin–polyethylene glycol (PEG)–epidermal growth factor (EGF) conjugate was immobilized onto the surface of avidin-modified adenovirus (ADV-Avi) via biotin–avidin interaction to deliver ADV specifically to EGF receptor over-expressing cancer cells.
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30423-3
Apr 01, 2011 · We recently demonstrated tumor-selective iodide uptake and therapeutic efficacy of radioiodine in neuroblastoma tumors after systemic nonviral polyplex-mediated sodium iodide symporter (NIS) gene delivery. In the present study, we used novel polyplexes based on linear polyethylenimine (LPEI), polyethylene glycol (PEG), and the synthetic peptide GE11 as an epidermal growth factor receptor (EGFR ...Author: Kathrin Klutz, David Schaffert, Michael J Willhauck, Geoffrey K Grünwald, Rudolf Haase, Nathalie Wun...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207138/
Among these potential antigens, epidermal growth factor receptor (EGFR) and the genetic deletion variant III (EGFRvIII) have been targeted by specific therapeutic approaches designed to block signaling or induce antitumor immune responses.Author: Kendra L. Congdon, Patrick C. Gedeon, Carter M. Suryadevara, Hillary G. Caruso, Laurence J.N. Cooper...
https://www.fasebj.org/doi/full/10.1096/fj.05-4058com
Dec 01, 2005 · Epidermal growth factor receptor (ErbB1, EGFR) is overexpressed in a variety of human cancer cells. It has been considered as a rational target for drug delivery. To identify novel ligands with spe...Author: Zonghai Li, Ruijiao Zhao, Xianghua Wu, Ye Sun, Ming Yao, Jinjun Li, Yuhong Xu, Jianren Gu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442602/
May 01, 2015 · Both epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor 1 (FGFR1) are overexpressed in the majority of human tumors, including ovarian cancer. To generate adenoviral vectors with improved tumor specificity, we generated a panel of Ad5 vectors with altered tropism for EGFR and FGFR, rather than the natural Ad5 receptor, hCAR.Author: Hanni Uusi-Kerttula, Mateusz Legut, James Anthony Davies, Rachel Jones, Emma Hudson, Louise Hanna, R...
https://www.researchgate.net/publication/7428278_Photochemically_enhanced_transduction_targeted_to_the_epidermal_growth_factor_receptor
Because Coxsackie-and adenovirus receptor expression is often reported to be higher in normal cells, the adenovirus has to be retargeted, e.g., with a growth factor targeting a certain receptor ...
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