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https://www.pnas.org/content/85/7/2403
Apr 01, 1988 · An approach for providing feedback control for polypeptide drugs in a polymeric controlled-release system uses a trigger molecule and a polymer-bound enzyme that, in the presence of that trigger molecule, will cause an acid or a base to form. When the pH inside the polymer system changes, the solubility of the drug shifts dramatically, which changes the diffusion or dissolution …Author: F Fischel-Ghodsian, L Brown, E Mathiowitz, D Brandenburg, R Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280001/
Enzymatically controlled drug delivery. F Fischel-Ghodsian , L Brown , E Mathiowitz , D Brandenburg , and R Langer Massachusetts Institute of Technology, Department of Applied Biological Sciences, Cambridge, 02139.Author: F Fischel-Ghodsian, L Brown, E Mathiowitz, D Brandenburg, R Langer
https://www.researchgate.net/publication/19875474_Enzymatically_Controlled_Drug_Delivery
Enzymatically Controlled Drug Delivery Article (PDF Available) in Proceedings of the National Academy of Sciences 85(7):2403-6 · May 1988 with 36 Reads How we measure 'reads'
https://www.researchgate.net/publication/229956029_Enzymatically_controlled_responsive_drug_delivery_systems
For instance, Goldbart et al. [14] developed an enzymatically controlled responsive drug delivery system consisting of a starch-based tablet incorporating a nonactive a-amylase and a protein. The ...
https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/pat.275
This paper discusses two approaches for the preparation of enzymatically controlled drug delivery systems: (i) a calcium‐responsive biodegradable drug delivery system based on a mixture of starch wit...Author: Riki Goldbart, Tamar Traitel, Smadar A. Lapidot, Joseph Kost
http://europepmc.org/articles/PMC280001
Apr 01, 1988 · Enzymatically controlled drug delivery. F Fischel-Ghodsian , L Brown , E Mathiowitz , D Brandenburg , and R Langer Massachusetts Institute of Technology, Department of Applied Biological Sciences, Cambridge, 02139.
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