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https://onlinelibrary.wiley.com/doi/10.1002/smll.201001389
Engineering Nanocarriers for siRNA Delivery. Shawn J. Tan. Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA. Search for more papers by this author. ... and aims to provide a guide towards engineering nanocarriers for effective siRNA delivery.Author: Shawn J. Tan, Pichamon Kiatwuthinon, Young Hoon Roh, Jason S. Kahn, Dan Luo
https://www.researchgate.net/publication/50273219_Engineering_Nanocarriers_for_siRNA_Delivery
Engineering Nanocarriers for siRNA Delivery. ... as well as the application of aptamers for molecular and cellular engineering, bioanalysis, and disease therapy. Owing to the predictable Watson ...
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201001389
Engineering Nanocarriers for siRNA Delivery. Shawn J. Tan. Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA. Search for more papers by this author. Pichamon Kiatwuthinon.Author: Shawn J. Tan, Pichamon Kiatwuthinon, Young Hoon Roh, Jason S. Kahn, Dan Luo
http://www.thno.org/v10p4557.htm
The intracellular or tumor microenvironment pH-responsive polymers have been applied for engineering pH-sensitive nanocarriers. ... Systemic siRNA delivery with a dual pH-responsive and tumor-targeted nanovector for inhibiting tumor growth and spontaneous metastasis in …
https://www.deepdyve.com/lp/wiley/engineering-nanocarriers-for-sirna-delivery-dqzsGmmnAa
Apr 04, 2011 · Read "Engineering Nanocarriers for siRNA Delivery, Small" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at …
https://jbioleng.biomedcentral.com/articles/10.1186/1754-1611-6-7
Dec 01, 2012 · Controlling gene expression via small interfering RNA (siRNA) has opened the doors to a plethora of therapeutic possibilities, with many currently in the pipelines of drug development for various ocular diseases. Despite the potential of siRNA technologies, barriers to intracellular delivery significantly limit their clinical efficacy. However, recent progress in the field of drug delivery ...Author: Ajit Thakur, Scott Fitzpatrick, Abeyat Zaman, Kapilan Kugathasan, Ben Muirhead, Gonzalo Hortelano, H...
https://www.ncbi.nlm.nih.gov/pubmed/29373841
Here, we review the recent strategies for siRNA delivery on the basis of smart nanocarriers by using stimuli-responsive materials. We highlight the rationales of how to design smart nanocarriers responsive to physiological and external stimuli to improve the delivery efficiency, targeting precision and gene silencing efficacy.Author: Penghui Zhang, Keli An, Xiaoman Duan, Hao Xu, Fei Li, Feng Xu
https://www.nature.com/articles/aps201712
Apr 10, 2017 · Engineering exosomes as refined biological nanoplatforms for drug delivery ... Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: effect of the degree of quaternization and ...Author: Xin Luan, Kanokwan Sansanaphongpricha, Ila Myers, Hongwei Chen, Hebao Yuan, Duxin Sun
https://www.sciencedirect.com/science/article/pii/S1359644617304294
Smart nanocarriers for siRNA delivery based on other metabolites. The aggressive proliferation and malignant metastasis of tumors also led to the dysregulation of other metabolites, such as oxygen, glucose, ATP and nucleic acids, which can be used to trigger on-command controlled drug release. Hypoxia is a general characteristic during tumor ...Author: Penghui Zhang, Keli An, Xiaoman Duan, Hao Xu, Fei Li, Feng Xu
https://pubs.acs.org/doi/abs/10.1021/acsnano.5b08145
In chemotherapy, it is a great challenge to recruit endogenous stimuli instead of external intervention for targeted delivery and controlled release; microRNAs are the most promising candidates due to their vital role during tumorigenesis and significant expression difference. Herein, to amplify the low abundant microRNAs in live cells, we designed a stimuli-responsive DNA Y-motif for ...Author: Penghui Zhang, Chen Wang, Jingjing Zhao, Anqi Xiao, Qi Shen, Linting Li, Jianxin Li, Junfeng Zhang, ...
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