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https://www.sciencedirect.com/science/article/pii/S0169409X07000981
If the purpose is antigen delivery and a MHC type I response, then delivery to the endoplasmic reticulum is the obvious goal. If the goal is invoked cell killing, for example, through a photosensitizer, then the answer is less obvious. The Golgi apparatus and endoplasmic reticulum are less well developed as apoptotic sites than the mitochondria.Author: Maria Teresa Tarragó-Trani, Brian Storrie
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718765/
Jul 17, 2013 · Drug discovery and drug delivery are two main aspects for treatment of a variety of disorders. However, the real bottleneck associated with systemic drug administration is the lack of target-specific affinity toward a pathological site, resulting in systemic toxicity and innumerable other side effects as well as higher dosage requirement for efficacy.Author: Niraj M Sakhrani, Harish Padh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134838/
Aug 10, 2007 · The existence of pathways for drug or antigen delivery to the endoplasmic reticulum and Golgi apparatus has been to a large extent an outcome of research on the trafficking of A/B type-bacterial or plant toxins such as Shiga toxin within the cell. The targeting properties of …Author: Maria Teresa Tarragó-Trani, Brian Storrie
https://www.thoughtco.com/endoplasmic-reticulum-373365
A cell's endoplasmic reticulum (ER) contains a network of tubules and flattened sacs. The ER performs multiple functions in both plant and animal cells. Endoplasmic reticulum has two major regions: smooth endoplasmic reticulum and rough endoplasmic reticulum. Rough ER contains attached ribosomes while smooth ER does not.Author: Regina Bailey
https://www.britannica.com/science/endoplasmic-reticulum
Endoplasmic reticulum, continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins. All eukaryotic cells contain an endoplasmic reticulum.
https://pubs.acs.org/doi/10.1021/acsami.9b18388
Cell membrane-coated nanocarriers have been developed for drug delivery due to their enhanced blood circulation and tissue targeting capacities; however, previous works have generally focused on spherical nanoparticles and extracellular barriers. Many living organisms with different shapes, such as rod-shaped bacilli and rhabdovirus, display different functionalities regarding tissue ...Author: Wei Zhang, Miaorong Yu, Ziyue Xi, Di Nie, Zhuo Dai, Jie Wang, Jie Wang, Kun Qian, Huixian Weng, Yong...
https://quizlet.com/141750943/endoplasmic-reticulum-flash-cards/
Rough endoplasmic reticulum has ribosomes attached to the cytoplasmic side of the membrane and the smooth endoplasmic reticulum lacks attached ribosomes. The smooth one is a tubule network and the rough one is a series of flattened sacs. Name of the space inside of the endoplasmic reticulum.
https://pubs.acs.org/doi/full/10.1021/acscentsci.9b01052
Antimicrobial peptides (AMPs) are part of the innate host defense system, and they are produced by living organisms to defend themselves against infections. Pardaxin is a cationic AMP with antimicrobial and antitumor activities that has potential to be used as a …Author: Xiaoling Yuan, Bing Qin, Hang Yin, Yingying Shi, Mengshi Jiang, Lihua Luo, Zhenyu Luo, Junlei Zhang,...
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/endoplasmic-reticulum-stress
Endoplasmic Reticulum Stress. Endoplasmic reticulum stress is a cellular mechanism to reduce protein synthesis in settings in which nutrient and oxygen delivery is not sufficient to fully process proteins.
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