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https://www.ncbi.nlm.nih.gov/pubmed/31814720
Nov 15, 2019 · Background: Cancer stem cells (CSCs) are responsible for cancer therapeutic resistance and metastasis. To date, in addition to surgery, chemotherapy, and radiotherapy, gene delivery has emerged as a potential therapeutic modality for ovarian cancer. Efficient and safe targeted gene delivery is complicated due to the tumor heterogeneity barrier.Author: Chun Liufu, Yue Li, Jiawei Tu, Hui Zhang, Jinsui Yu, Yi Wang, Pintong Huang, Zhiyi Chen
https://www.sciencedirect.com/science/article/pii/S0378517319308476
Engineered extracellular vesicles with synthetic lipids via membrane fusion to establish efficient gene delivery. Author links open overlay panel Yong-Yu Jhan Daniel Prasca-Chamorro Guillermo Palou Zuniga David Mitchell Moore Shreedevi Arun Kumar Akhilesh K. Gaharwar Corey J. Bishop. Show more.Author: Yong-Yu Jhan, Daniel Prasca-Chamorro, Guillermo Palou Zuniga, David Mitchell Moore, Shreedevi Arun K...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC110499/
Jun 01, 1998 · Efficient in vivo gene delivery by SIN vectors. The results described above indicated that the inactivation design did not interfere with the transduction of cellular targets in vitro by HIV-derived vectors. The performance of SIN vectors was assayed in an in vivo delivery model that demands high efficiency of gene transfer and expression.Author: Romain Zufferey, Thomas Dull, Ronald J. Mandel, Anatoly Bukovsky, Dulce Quiroz, Luigi Naldini, Didie...
https://www.sciencedirect.com/science/article/pii/S0168365903004127
Chitosan is considered to be a good candidate for the gene delivery system since it is already known as a biocompatible, biodegradable, and low toxic material with high cationic charge potential. However, the use of chitosan for gene delivery is limited due to low transfection efficiency.Author: Tae Hee Kim, Jong Eun Ihm, Yun Jaie Choi, Jae Woon Nah, Chong Su Cho
https://www.nature.com/articles/s41598-018-35463-8
Dec 12, 2018 · Efficient gene delivery technologies play an essential role in the gene functional analyses that are necessary for basic and applied researches. Mosquitoes are ubiquitous insects, responsible for ...Author: Nenavath Gopal Naik, Yu-Wen Lo, Tzong-Yuan Wu, Chang-Chi Lin, Szu-Cheng Kuo, Yu-Chan Chao, Yu-Chan C...
http://www.nature.com/articles/doi:10.1038/nn.4593
Jun 26, 2017 · Adeno-associated viruses (AAVs) are commonly used for in vivo gene transfer. Nevertheless, AAVs that provide efficient transduction across specific organs or …Author: Ken Y. Chan, Min J. Jang, Bryan B. Yoo, Alon Greenbaum, Namita Ravi, Wei Li Wu, Luis Sánchez-Guardad...
https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-0712-8
Mar 02, 2018 · However, CD105-targeted agents combining cancer drug/gene delivery and imaging in a single nanomaterial have not been widely reported to date. This study describes an efficient targeted CD105 gene-delivery system that combines imaging and therapeutic modalities in a single nanoparticle.Author: Huiqin Zhuo, Baoshi Zheng, Jianming Liu, Yong Huang, Huiling Wang, Duo Zheng, Naiquan Mao, Jinyu Men...
https://www.researchgate.net/publication/260395546_Efficient_in_vivo_gene_delivery_using_modified_Tat_peptide_with_cationic_lipids
Efficient in vivo gene delivery using modified Tat peptide with cationic lipids ... Virus-mediated gene delivery shows promise for the treatment of chronic pain. ... cysteines to develop a more ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30019-4
Apr 04, 2018 · The Sleeping Beauty (SB) transposon system is a non-viral gene delivery platform that combines simplicity, inexpensive manufacture, and favorable safety features in the context of human applications. However, efficient correction of hematopoietic stem and progenitor cells (HSPCs) with non-viral vector systems, including SB, demands further refinement of gene delivery techniques.Author: Marta Holstein, Cristina Mesa-Nuñez, Csaba Miskey, Elena Almarza, Valentina Poletti, Marco Schmeer, ...
https://pubs.acs.org/doi/10.1021/acscentsci.9b01052
The efficient gene delivery mechanism of the viruses represented by SV40 is of great significance for use in the design and preparation of highly efficient nonviral gene vectors. With reference to the intracellular nonlysosomal transport pathway of the SV40 virus, ...Author: Xiaoling Yuan, Bing Qin, Hang Yin, Yingying Shi, Mengshi Jiang, Lihua Luo, Zhenyu Luo, Junlei Zhang,...
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