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https://www.sciencedirect.com/science/article/pii/S2211383513000178
Effective drug delivery to the inner ear via the intratympanic route also relies on the contact time of the drug solution (or drug delivery system) with the RWM. Unfortunately, large portions of the administered drugs are usually eliminated through the Eustachian tube following intratympanic drug delivery.Author: Hongzhuo Liu, Hongzhuo Liu, Jinsong Hao, Kevin S. Li
https://www.academia.edu/14504473/Drug_delivery_to_the_ear
Drug delivery to the ear is used to treat conditions of the middle and inner ear such as acute and chronic otitis media, Ménière's disease, sensorineural hearing loss and tinnitus. Drugs used include antibiotics, antifungals, steroids, local
https://www.ncbi.nlm.nih.gov/pubmed/23323784
Localized treatments to the ear have the advantages of targeted drug delivery allowing higher therapeutic doses and minimizing systemic side effects. The ideal scenario would be a carrier system that could cross the intact tympanic membrane loaded with drugs or biochemical agents for the treatment of middle and inner ear conditions.Author: E Hoskison, M Daniel, S Al-Zahid, KM Shakesheff, R Bayston, JP Birchall
https://www.researchgate.net/publication/232257568_Drug_delivery_systems_An_updated_review
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222974/
Drug delivery – Clinically viable therapeutic options. There are a number of options in terms of potential clinically viable methods for drug delivery to the cochlea (see [42,43]). These include drug-eluting polymers which can provide slow-release drug delivery based …Author: Andrew K Wise, Andrew K Wise, Lisa N Gillespie, Lisa N Gillespie
https://www.researchgate.net/publication/234156423_Drug_delivery_to_the_ear
Drug delivery to the ear is used to treat conditions of the middle and inner ear such as acute and chronic otitis media, Ménière's disease, sensorineural hearing loss and tinnitus.
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