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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769721/
DUROS ® delivery technology consists of sterile, nonbiodegradable, single-use devices for continuous, subcutaneous administration of therapeutic molecules at steady rates. DUROS delivery technology is capable of delivering a wide range of therapeutic molecules for durations ranging from 3 to 12 months.Author: Catherine M. Rohloff, Thomas R. Alessi, Bing Yang, Janice Dahms, John P. Carr, Scott D. Lautenbach
http://www.diabetesincontrol.com/wp-content/uploads/PDF/ntarcia_platform_technology.pdf
Intarcia’s platform technology is known as the DUROS® subcutaneous delivery system. The DUROS system is comprised of a small, matchstick-sized osmotic pump that is inserted subcutaneously (just beneath the skin) to deliver a slow and consistent flow of medication.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932646/
Jun 24, 2016 · The DUROS system by Alza was developed in 2000 for leuprolide delivery for the treatment of prostate cancer (Fig. 3A). A notable characteristic of this device is its ability to release drug at a constant rate.Author: Seung Ho Lee, Young Bin Choy
http://ijpsr.com/bft-article/a-review-on-osmotic-pump-drug-delivery-system/?view=fulltext
ABSTRACT: Drug release from novel drug delivery systems are desired to be controlled at target site in effective concentration for required therapeutic action with predictable plasma concentrations, unlike conventional ones, thereby reducing the dose, dosage frequency, toxic adverse effects, reduction of blood level fluctuations, improved patient compliance and minimization of drug accumulation. As this can be achieved by the phenomenon called osmosis, osmotic pump drug delivery systems …
http://www.authorstream.com/Presentation/pavan22raju-1931893-implants-drug-delivery-systems/
Sep 15, 2013 · Implantable drug delivery systems are designed to transmit drugs and fluids into the bloodstream without the repeated insertion of needles. Implantable drug delivery systems are placed completely under the skin usually in a convenient but inconspicuous location.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854252/
In summary, future efforts for ideal drug delivery systems for IP chemotherapy should take into consideration the need for tumor specificity, efficient tissue penetration, cellular uptake and intracellular residence of a drug. In addition, when a new drug delivery system is developed for IP therapy, the biocompatibility of the carrier materials should be warranted so that complications due to the tissue …Author: Gaurav Bajaj, Yoon Yeo
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576846/
Duros® was explored for the delivery of sufentanil, an analgesic, using the Chronogesic® Pain Therapy System for chronic pain management [ 11 ] and for exenatide (type 2 diabetes) and ω-interferon (Hepatitis C) [ 102 ].Author: Ellis Meng, Tuan Hoang
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past …
https://www.slideshare.net/shreeraj9183/osmotic-drug-delivery-system-44306707
Feb 05, 2015 · Osmotic drug delivery system. 1. 4. INTRODUCTION Osmotic drug delivery uses the osmotic pressure of drug or other solutes (osmogens or osmagents) for controlled delivery of drugs. Osmotic drug delivery has come a long way since …
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