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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Interestingly pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs and up to recently did not realize that carrier …Author: Wim H De Jong, Paul Ja Borm
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES — Considerable research and development is devoted to improving drug delivery through the use of nanoparticles. Although the definition of nanoparticle has become murky, typically they are defined being in the size range of 100 nm and below, Dynamic light scattering (DLS) is the preferred method in this size ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.frontiersin.org/articles/10.3389/fphar.2016.00084/full
Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting Bing Lu 1 , Xiaojia Huang 1 , Jingxin Mo 1,2* and Wei Zhao 1,2* 1 Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, ChinaAuthor: Bing Lu, Xiaojia Huang, Jingxin Mo, Wei Zhao
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.
https://www.nih.gov/news-events/nih-research-matters/chemotherapy-using-nanoparticles
A new drug delivery technique may hold promise for more efficient cancer therapies. The technique involves storing a cancer drug inside tiny objects called nanoparticles. Using this method, researchers were able to shrink tumors in mice while using smaller doses of the drug to reduce harmful side effects.
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues. Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.sciencedirect.com/science/article/pii/S0142961213012647
Nanoparticles based on biodegradable or non-biodegradable materials such as natural or synthetic polymers, lipids and metals have received considerable interest as drug delivery vehicles , , . Poly (lactide-co-glycolide) (PLGA) is a FDA approval biodegradable polymer which has been widely used as a model molecular biomaterial for synthesis of nanoparticles for sustained, controlled and targeted drug …Author: Xudong Zhang, Yichen Dong, Xiaowei Zeng, Xin Liang, Xiaoming Li, Wei Tao, Hongbo Chen, Yuyang Jiang,...
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