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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The use of nanoparticles as drug carrier may reduce the toxicity of the incorporated drug. In general the toxicity of the whole formulation is investigated while results of the nanoparticles itself are not described. So, discrimination between drug and nanoparticle toxicity cannot be made.Author: Wim H De Jong, Paul Ja Borm
https://www.entegris.com/content/dam/product-assets/nicompnanodlszlssystems/appnote-drug-delivery-using-nanoparticles-10549.pdf
DRUG DELIVERY USING NANOPARTICLES — Considerable research and development is devoted to improving drug delivery through the use of nanoparticles. Although the definition of nanoparticle has become murky, typically they are defined being in the size range of 100 nm and below, Dynamic light scattering (DLS) is the preferred method in this size ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.researchgate.net/publication/23155652_Drug_delivery_and_nanoparticles_Applications_and_hazards
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.
https://www.researchgate.net/publication/264163597_Nanoparticles_in_drug_delivery_Mechanism_of_action_formulation_and_clinical_application_towards_reduction_in_drug-associated_nephrotoxicity
Introduction: Over the past few decades, nanoparticles (NPs) have gained immeasurable interest in the field of drug delivery. Various NP formulations have been disseminated in drug development in ...
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues. Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769170/
Aug 30, 2010 · Metal nanoparticles are attractive options for drug and contrast agent delivery because they are a stable platform on which multiple functionalities can be grafted, some can be imaged directly, and certain formulations allow magnetic-directed guidance [110,111]. The latter can be used to localize drugs, genes, and contrast agents to a specific ...Author: Siti M. Janib, Ara S. Moses, J. Andrew MacKay
https://www.sciencedirect.com/science/article/pii/B9780128136898000021
Nanoparticle drug delivery systems (NPDDS) achieve superior entry for the particles inside the body, as their size permits conveyance by means of intravenous infusion or different courses. Another important use of the NPDDS is in the production of the antibodies …Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha
https://pubs.acs.org/doi/abs/10.1021/acsnano.7b08620
Our study focuses on the design of sophisticated nanoparticle assemblies with multiple and synergistic functions that have the potential to advance sensing and drug delivery in cells. Multiplexed mRNA Sensing and Combinatorial-Targeted Drug Delivery Using DNA-Gold Nanoparticle Dimers ACS NanoAuthor: Maria Eleni Kyriazi, Davide Giust, Afaf H. El-Sagheer, Afaf H. El-Sagheer, Peter M. Lackie, Otto L. ...
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