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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424884/
Therefore, their use is rapidly expanding, especially for drug delivery to the lungs. Chitosan, one of the most famous and commonly used micelle, was recently used as nanoparticle to deliver drug to the lungs, especially for drugs with high first pass phenomena such as isoniazid.
https://www.researchgate.net/publication/230733979_The_lungs_and_drug_delivery
Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung both for local and systemic treatment.
https://www.ondrugdelivery.com/pulmonary-delivery-antimicrobial-peptides/
A particular advantage is the possibility for local drug delivery in the lung. The extension of using similar nanoformulation platforms for delivery of antimicrobial peptides holds promise for the future and is currently under development in FORMAMP.
https://www.ondrugdelivery.com/scaling-high-dose-delivery-lungs/
João Ventura Fernandes, Gonçalo Rebelo de Andrade and Peter Villax describe the scaling up of the currently marketed TwinCaps® inhaler into the new TwinMax™ design for high-dose delivery of challenging drug-alone formulations in single to short-term treatments and emergency situations.
https://aerosol-soc.com/events/ddl2018/
Drug Delivery to the Lungs 2018. 12th Dec - 14th Dec 2018. Edinburgh. ... The Aerosol Society recognises the importance of our diverse community and believe that to produce the best quality science we must encourage a proactive and inclusive approach to equality. This can be achieved by developing and retaining a diverse range of talented ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013600/
Apr 08, 2014 · 1. Introduction. Lungs are an attractive target for the pulmonary administration of active pharmaceutical ingredients (APIs) in the form of various drug delivery systems [1–3].Additionally, this route offers many advantages over conventional per oral administration, such as a high surface area with rapid absorption due to high vascularization and circumvention of the first pass effect [].Author: Mukta Paranjpe, Christel C. Müller-Goymann
https://www.meddeviceonline.com/doc/developing-a-smart-inhaler-for-optimal-drug-delivery-0001
Dec 16, 2019 · Another challenge with inhaled drug delivery is potential adverse effects related to device design or formulations. For instance, DPIs tend to form aggregates that are not respirable and therefore limit the amount of drug taken up via the lungs.
https://www.japsonline.com/admin/php/uploads/498_pdf.pdf
rapid removal of drug from the lungs or due to drug metabolism. Necessitates frequent dosing (Ozer, 2007). Uptake of inhaled drug after inhalation therapy There are several advantages in delivering drugs, to the lungs including a non invasive method of delivery; the surface area of the lung is between 80 m2 and 140 m2, which is about half the
https://www.pharmatutor.org/articles/targeted-drug-delivery-systems-lung-cancer
Targeted drug delivery of anticancer drug on tumor site in lungs improves the therapeutic effect because it decreases the systemic exposure of drug. Lungs provide large surface area (about 100m 2) and high vascularization which rapidly distribute the molecules.Author: Abdul Waheed, Ankit Gupta, Parth Patel
https://aerosol-soc.com/events/ddl2017/
Drug Delivery to the Lungs Conference (DDL) 6th Dec - 8th Dec 2017. ... DDL continues to be the primary forum to hear / see the latest development in the drug delivery sector. It provides delegates and exhibitor a unique platform to present and show off there latest technologies.” ...
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