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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
Concentration of drug available in the precorneal area acts as a driving force for its passive diffusion across cornea. However, for efficient ocular drug delivery with eye drops, high corneal permeation with longer drug cornea contact time is required. Several efforts have been made toward improving precorneal residence time and corneal ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Ocular Drug Delivery AswAni Dutt VADlApuDi, Kishore CholKAr, supriyA reDDy DAsAri, AnD Ashim K. mitrA CHAPTER OBJECTIVES Upon completing this chapter, the reader should be able to Describe the anatomy and physiology of the eye. Understand the importance of various routes of drug administration to the eye. Describe various barriers to ocular drug delivery and constraints with
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug delivery to the eye is a complex process. As a self-contained system, the eye is unique in the body in many ways that affect pharmacology and toxicology. It includes several different cell types, and functions as a complete, self-contained system. The rate and efficacy of …
https://www.glaucoma.org/treatment/alternative-drug-delivery-systems-for-glaucoma.php
Much work needs to be done before we know exactly how well these new drug delivery options will perform. But it is gratifying to know that new and better ways to treat glaucoma are on the way. Hopefully, this kind of alternative drug delivery technology will result in …
https://www.nature.com/articles/eye201182
Apr 08, 2011 · Download PDF. Glaucoma: drugs and targets ... Search terms included: polymer and drug and eye, glaucoma and polymer, glaucoma and drug, eye …Author: Erin Baker Lavik, M. H. Kuehn, Y. H. Kwon
http://drugdelivery.chbe.gatech.edu/Papers/1998/Prausnitz%20J%20Pharm%20Sci%201998.pdf
REVIEW ARTICLE Permeability of Cornea, Sclera, and Conjunctiva: A Literature Analysis for Drug Delivery to the Eye MARK R. PRAUSNITZ* AND JEREMY S. NOONAN Contribution from Schools of Chemical Engineering and Biomedical Engineering, Georgia Institute of …
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
PDF INTRODUCTION Eye is most interesting organ due to its drug disposition characteristics. ... OCULAR DRUG DELIVERY SYSTEM – A REVIEW ... The first one is …
http://www.thepharmajournal.com/vol1Issue12/Issue_feb_2013/1.1.pdf
successful and advanced ocular drug delivery systems. The goal of pharmacotherapeutics is the attainment of an effective drug .concentration at the intended site of action for a desired period of time. Eye, as a portal for drug delivery is generally used for the local therapy as against systemic therapy in order to avoid the risk of eye
https://www.eyeworld.org/article-drug-delivery-systems-for-glaucoma
GLAUCOMA Device focus Drug delivery systems for glaucoma by Michelle Dalton EyeWorld Contributing Writer Bimatoprost SR in the anterior chamber Source: Allergan The expanding options will help glaucoma specialists manage patients IOP better For years, the mainstay of glaucoma treatment has been topical eye drops, laser angle treatment, and surgery (trabeculectomy, mostly)
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