We have collected information about Drug Delivery To Brain Through Nasal Route for you. Follow the links to find out details on Drug Delivery To Brain Through Nasal Route.
https://www.ncbi.nlm.nih.gov/pubmed/28887135
Dec 28, 2017 · Intranasal route of transportation directly delivers the drugs to brain without systemic absorption, thus avoiding the side effects and enhancing the efficacy of neurotherapeutics. Over the last several decades, different drug delivery systems (DDSs) …Author: Abdur Rauf Khan, Mengrui Liu, Muhammad Wasim Khan, Guangxi Zhai
https://www.sciencedirect.com/science/article/pii/S0168365917308258
Targeting of drugs deep into nasal mucosa is the utmost requirement of targeted nasal drug delivery to brain. Nasal drops and traditional sprays are unable to deposit drug in olfactory epithelium. These traditional devices are useless for targeting brain through olfactory pathway.Author: Abdur Rauf Khan, Mengrui Liu, Muhammad Wasim Khan, Guangxi Zhai
https://www.ncbi.nlm.nih.gov/pubmed/31660815
Oct 29, 2019 · Efforts to directly target the brain by olfactory as well as trigeminal nerve pathway, bypassing BBB have grown significantly in recent times. Intranasal route of transportation of the drug encompasses ability for the delivery of drug directly to brain, improve site specificity in the brain and avoiding systemic side effects.Author: Kanchan Kashyap, Rahul Shukla
https://www.sciencedirect.com/science/article/pii/S0361923018303678
Transmucosal delivery of drugs through olfactory or trigeminal pathways to brain bypassing the BBB is referred as the direct IN drug transportation to brain. This is the only route through which brain is in connection with the outside environment (Mistry et al., 2009).Author: Franciska Erdő, Luca Anna Bors, Dániel Farkas, Ágnes Bajza, Sveinbjörn Gizurarson
https://www.slideshare.net/ishanipandit034/brain-targeted-drug-delivery-through-nasal-route
Mar 01, 2015 · brain targeted drug delivery through nasal route 1. brain targeted drug delivery through nasal route guided by: dr. dhaivat parikh pharmaceutical technology & biopharmaceutics prepared by: ishani pandit (14mph109) pharmaceutical technology & biopharmaceutics 3/1/2015 1
https://en.wikipedia.org/wiki/Nasal_administration
Nasal administration is a route of administration in which drugs are insufflated through the nose. It can be a form of either topical administration or systemic administration, as the drugs thus locally delivered can go on to have either purely local or systemic effects.
https://www.pharmatutor.org/articles/brain-targeting-drug-delivery-system-through-nasal-cavity
Which formulation is better to target brain through nose would also be considered, device for effective nasal to brain drug delivery is also a develop thrust area for device companies. By nasal route BBB can be avoided, rapid action can be given in diseases like migraine, brain tumor, Alzheimer, Parkinson’s disease and hormone replacement.
https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
NASAL DRUG DELIVERY RAPID ONSET VIA A CONVENIENT ROUTE ... adenoids can also all be accessed through intranasal delivery. Furthermore, for direct “nose-to-brain delivery”, by-passing the blood-brain barrier, the olfactory region enables drugs to enter the cerebrospinal
http://jpet.aspetjournals.org/content/370/3/593
Sep 01, 2019 · Nose-to-Brain Mechanism of Delivery. For the purposes of drug delivery, the nasal cavity is divided into the respiratory area and the olfactory area, with the latter situated high up in the nares and the former closer to the nostrils (Sahin-Yilmaz and Naclerio, 2011).The nasal epithelium is well vascularized (Sahin-Yilmaz and Naclerio, 2011), and, within the olfactory area, olfactory neurons ...Author: Zian Wang, Guojun Xiong, Wai Chun Tsang, Andreas G. Schätzlein, Ijeoma F. Uchegbu
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