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https://www.researchgate.net/publication/279408805_Brain_targeting_Drug_Delivery_System_A_Review
In the application of nanoparticles for brain targeting, their drug release profiles have been reported to be sustained, slow, and controlled, thereby overcoming toxicity.
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
https://www.researchgate.net/publication/297283078_Targeted_Drug_Delivery_A_Review
Drug delivery vehicles transport the drug either within or in the vicinity of target. An id eal drug delivery vehicle is supposed to cross even stubborn sites such as a blood brain barrier.
https://sites.ualberta.ca/~csps/JPPS6(2)/A.Misra/delivery.pdf
Drug delivery to the central nervous system: a review. Ambikanandan Misra, Ganesh S., Aliasgar Shahiwala Pharmacy Department, M.S. University of Baroda Shrenik P. Shah Sun Pharma Advanced Research Center, Baroda Received 16 June 2003, Revised 26 June 2003, Accepted 5 August 2003 Abstract The brain is a delicate organ, and evolution built
https://link.springer.com/book/10.1007%2F978-1-4614-9105-7
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB. It contains cutting-edge methods for studying …
http://jpet.aspetjournals.org/content/370/3/593
Sep 01, 2019 · Nose-to-Brain Mechanism of Delivery. For the purposes of drug delivery, the nasal cavity is divided into the respiratory area and the olfactory area, with the latter situated high up in the nares and the former closer to the nostrils (Sahin-Yilmaz and Naclerio, 2011).The nasal epithelium is well vascularized (Sahin-Yilmaz and Naclerio, 2011), and, within the olfactory area, olfactory neurons ...Author: Zian Wang, Guojun Xiong, Wai Chun Tsang, Andreas G. Schätzlein, Ijeoma F. Uchegbu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199953/
May 14, 2018 · The exact mechanism of drug transport from the nasal cavity to the brain is still a different issue among scientists although; it was supposed to follow the combined way to enter into the brain. Moreover, the drug transport mechanism depends upon various factors such as nature of the drug, type of delivery system or dosage form, a device used ...Author: Amit Alexander, Shailendra Saraf
https://www.mdpi.com/1999-4923/11/2/84/pdf
Nose-to-brain drug delivery is a painless, non-invasive administration route that can be used to deliver therapeutic agents into the brain by bypassing the BBB [10,14–17]. These drug administration pathways are characterized by many advantages such as increasedAuthor: Maria Cristina Bonferoni, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, Elisabetta Gavini, Giovan...
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