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https://www.ophthalmicprofessional.com/issues/2019/may-2019/advances-in-drug-delivery-systems
May 01, 2019 · While much of the current activity in advanced drug delivery systems focuses on cataract surgery, clinicians are sure to see pharmaceutical companies address other conditions. For instance, injections to address glaucoma are on the horizon. These post-procedure delivery methods can enhance the patient experience.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061492/
Periocular drug delivery using the transscleral absorption pathway is one of the safest means of achieving consistent therapeutic drug concentrations in the inner coat of the posterior segment (Table 1). 5,6,24 Periocular drug delivery systems, however, require drugs to pass through several layers of ocular tissue (episclera, sclera, choroid, Bruch's membrane, and RPE) to reach the retina or vitreous …Author: Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chad...
https://www.glaucoma.org/treatment/new-medication-delivery-systems-for-glaucoma.php
On the Eye, In the Eye, Around the Eye. The basic idea of drug delivery systems for glaucoma is to apply, insert, or inject medication to the eye that will release over weeks or months. Various delivery approaches are being developed that can be categorized as: on the eye, in the eye, and around the eye.
https://www.sciencedirect.com/science/article/pii/S1350946297000025
To overcome the disadvantages of eye-drops, various ophthalmic drug delivery systems, such as hydrogels, micro-and nanoparticles, liposomes and collagen shields have been investigated. Drug delivery, as it pertains to the eye, is a generic term which is defined broadly as represent- ing an approach to controlling and ultimately optimizing delivery of the drug to its target tissue in the eye.Author: Chrystèle Le Bourlais, Liliane Acar, Hosein Zia, Pierre A. Sado, Thomas Needham, Roger Leverge
https://eye.hms.harvard.edu/topic/drug-delivery-medical-devices
We developed a contact lens based dexamethasone delivery system (Dex-DS) that achieved sustained drug delivery to the retina at therapeutic levels. Dex-DS consists of a dexamethasone-polymer film encapsulated inside a contact lens.
https://www.nature.com/articles/s41433-020-0809-0
Feb 18, 2020 · Recent advances in pharmacological agents have led to successful treatment of a variety of retinal diseases such as neovascular age-related macular degeneration (AMD), diabetic macular oedema (DMO ...Author: Jennifer J. Kang-Mieler, Kayla M. Rudeen, Wenqiang Liu, William F. Mieler
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