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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Nanoparticles and drug delivery. Drug delivery and related pharmaceutical development in the context of nanomedicine should be viewed as science and technology of nanometer scale complex systems (10–1000 nm), consisting of at least two components, one of which is a pharmaceutically active ingredient (Duncan 2003; Ferrari 2005), although nanoparticle formulations of the drug itself are also ...Author: Wim H De Jong, Paul Ja Borm
https://www.nanowerk.com/spotlight/spotid=51090.php
Sep 18, 2018 · Sep 18, 2018: Nanotechnology based drug delivery systems for nanomedicine (Nanowerk Spotlight) Development of an effective approach for delivering a new drug is as important as inventing a new drug.Even if a developed new drug has excellent pharmacokinetic and therapeutic properties, it shows its potential activity in the body effectively only when it is exactly targeted to specific molecules.
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Administration of substances directly into the cerebrospinal fluid (CSF) that surrounds the brain and spinal cord is one approach that can circumvent the blood-brain barrier to enable drug delivery to the central nervous system (CNS).Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292417/
Feb 23, 2012 · A newly developed nanomaterial-based drug-delivery system has to perform at various levels; only then can it reach its final destination of application to alleviate human ailments. The growing list of approved NPs in medicine (Figure 6) and newer agents in …
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The use of ideal nano-drug delivery system is decided primarily based on the biophysical and biochemical properties of the targeted drugs being selected for the treatment . However, problems such as toxicity exhibited by nanoparticles cannot be ignored when considering the use of nanomedicine.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://link.springer.com/article/10.1007%2Fs40089-014-0094-7
Feb 20, 2014 · Nanomedicine and drug delivery: a mini review ... for insoluble drugs. For example, the trans-retinoic acid nanoparticle coated by CaCO 3 was developed as a new drug delivery system, which on spray drying formed aggregates. ... Tracking of nanomedicine from the systemic to sub-cellular level becomes essential.Author: Agha Zeeshan Mirza, Farhan Ahmed Siddiqui
https://en.wikipedia.org/wiki/Nanomedicine
The efficacy of drug delivery through nanomedicine is largely based upon: a) efficient encapsulation of the drugs, b) successful delivery of drug to the targeted region of the body, and c) successful release of the drug. [citation needed] Drug delivery systems, lipid-or polymer-based nanoparticles, can be designed to improve the ...
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.
https://www.alliedacademies.org/articles/nanomedicine-drug-delivery-system.pdf
of drug molecules where they are needed in the body and where they will do the most good. Drug delivery focuses on maximizing bioavailability both at specific places in the body and over a period of time. This can potentially be achieved by molecular targeting by nanoengineered devices.6-7 Current problems for nanomedicine involve understandingAuthor: S.B. Somwanshi, R.T. Dolas, S.S Siddheshwar, A.N. Merekar, R.K. Godge, S. R. Pattan
https://www.prescouter.com/2020/03/nanomedicine-using-smart-nanoparticles-for-better-drug-delivery/
An efficient drug delivery system should both retain the drugs within the vehicle and then subsequently release them when they are proximal to the desired location, and nanoparticles can accomplish this. However, in 2016, it was reported that only 0.7% of the introduced nanomedicine is eventually found in the targeted tumor.
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