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https://www.researchgate.net/publication/277705442_Drug_Delivery_Strategies_for_Poorly_Water-Soluble_Drugs
Nanoparticles are a drug delivery platform that can enhance the efficacy of active pharmaceutical ingredients, including poorly-water soluble compounds, ionic drugs, proteins, peptides, siRNA and ...
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118444726
Jan 21, 2013 · Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.
https://www.researchgate.net/publication/277693709_Drug_Delivery_Strategies_for_Poorly_Water-Soluble_Drugs
Request PDF Drug Delivery Strategies for Poorly Water-Soluble Drugs Antisolvent precipitation is a widely used technique for the manufacture of nanosuspensions of poorly water-soluble drugs.Author: Dennis Douroumis
https://www.sciencedirect.com/science/article/pii/S2211383515001069
About 40% of drugs with market approval and nearly 90% of molecules in the discovery pipeline are poorly water-soluble. With the advent of various insoluble drug delivery technologies, the challenge to formulate poorly water soluble drugs could be achieved.Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.wiley.com/en-us/Drug+Delivery+Strategies+for+Poorly+Water+Soluble+Drugs-p-9781118444672
Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of ...
https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118444726.ch4
The chapter concludes with a summary of in vivo data on the improvement in oral bioavailability of poorly soluble drugs through the use of solid lipid nanoparticle dispersions and the application of such systems in parenteral drug delivery, with a special focus on pharmacokinetics and biodistribution.Author: Sonja Joseph, Heike Bunjes
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