Drug Delivery Silicone Matrix

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Silicones for Drug-Delivery Applications MDDI Online

    https://www.mddionline.com/silicones-drug-delivery-applications
    May 01, 2006 · Silicones for Drug-Delivery Applications. ... In some devices, the drug is incorporated into a silicone matrix core, or reservoir, and the outer layer of silicone (without pharmaceutical agents incorporated) controls the release on the device. Such information …

Research and development of a silicone letrozole-releasing ...

    https://www.sciencedirect.com/science/article/pii/S0093691X20301102
    With the intent of developing a device that will provide more uniformity in drug delivery compared to the wax dip-coat intravaginal devices used previously the objective of the present study was to determine if letrozole-impregnated silicone will provide an effective drug …Author: E.M. Zwiefelhofer, B.M. Davis, G.P. Adams

Ear Cubes for local controlled drug delivery to the inner ...

    https://www.sciencedirect.com/science/article/pii/S0378517316302782
    Ear Cubes (Fig. 2, right hand side) were prepared by injecting the “silicone kit − drug” mixture into customized molds (Neurelec, Vallauris, France) using a texture analyzer (TAXT plus, Stable Micro Systems, Surrey, UK).Two types of molds were used to prepare “smaller” and “larger” Ear Cube implants. The geometries and dimensions of the latter are illustrated in Fig. 1.Author: M. Gehrke, J. Sircoglou, D. Gnansia, G. Tourrel, JF willart, Florence Danede, E. Lacante, C. Vincent...

ONdrugDelivery - ONdrugDelivery - drug delivery industry ...

    https://www.ondrugdelivery.com/
    ONdrugDelivery, a leading drug delivery b2b industry publication, exists to provide its readers throughout global pharma and biopharma, with the latest, most pertinent, high-quality industry information, intelligence and insights we possibly can, about the ideas, technologies, services and products the drug delivery sector is developing, across drug delivery devices and formulations.%

Porous silicon in drug delivery devices and materials

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710886/
    Aug 17, 2008 · Porous silicon in drug delivery devices and materials ... or the supporting porous Si matrix is degraded. For drug delivery this introduces a complication in that the drug may not release from the linker, resulting in a modified version of the drug being introduced into the body. ...Author: Emily J. Anglin, Lingyun Cheng, William R. Freeman, Michael J. Sailor

Implantable Drug Delivery Devices An Overview

    https://promedmolding.com/implantable-drug-delivery-devices-overview/
    Dec 18, 2017 · Silicones have long been a material of choice for drug delivery given their extreme chemical inertness, range of stable mechanical properties, and ability to compound various APIs within the matrix. The rate of release is generally proportional to the loading of drug within the silicone, typically 5-50% by weight.

Silicone Adhesives for Transdermal Drug Delivery Systems

    https://www.dupont.com/content/dam/Dupont2.0/Products/healthcaresolutions/literature/52-1070C-01.pdf
    Transdermal drug delivery patches are designed to deliver a therapeutically effective amount of drug across a patient’s skin to efficiently treat targeted diseases. Transdermal patches typically involve a pressure sensitive adhesive used as a patch fixation system and/or drug matrix.

Silicone adhesive matrix of verapamil hydrochloride to ...

    https://www.ncbi.nlm.nih.gov/pubmed/24022347
    Silicone adhesive matrix of verapamil hydrochloride to provide pH-independent sustained release. Tolia G, Li SK. Providing pH-independent oral release of weakly basic drugs with conventional matrix tablets can be challenging because of the pH-dependent solubility characteristics of the drugs and the changing pH environment along the ...Author: Gaurav Tolia, S. Kevin Li

ect of Di erent Pressure-Sensitive Adhesives on ...

    https://www.mdpi.com/1999-4923/12/3/209/pdf
    Transdermal delivery systems (TDSs) are designed to provide a controlled and prolonged delivery of the drug substance across the skin and into the systemic circulation [1,2]. TDS can be generally categorized into matrix-type and reservoir-type delivery systems. Matrix-type TDS contain the activeAuthor: Behnam Dasht Bozorg, Ajay K. Banga

Matrix Type Drug Delivery System: A Review

    http://jpsbr.org/index_htm_files/3_1151.pdf
    sustained release or controlled release drug delivery systems. 11 Matrix systems are widely used for the purpose of sustained release. It is the release system which prolongs and controls the release of the drug that is dissolved or dispersed. In fact, aFile Size: 679KB

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