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https://www.sciencedirect.com/science/article/pii/S0169409X12000087
Virus-like particles (VLPs) based on biological building blocks have become an emerging type of nanocarriers for targeted drug delivery. Viruses have the unique advantage of structural uniformity and their chemical and conformational structures can be produced precisely and in large quantities.Author: Y. Ma, Y. Ma, R.J.M. Nolte, Jeroen Johannes Lambertus Maria Cornelissen
https://www.researchgate.net/publication/248827796_Drug_delivery_Like_a_virus
Download Citation Drug delivery: Like a virus The development of nanocarriers to deliver drugs — in particular, for treating cancer — to specific cells in the body is the subject of ...Author: Gemma Moxham
https://www.news18.com/news/lifestyle/a-virus-inspired-method-for-drug-delivery-to-the-brain-developed-says-study-2343131.html
Oct 12, 2019 · A Virus-inspired Method for Drug Delivery to the Brain Developed, Says Study The study noted that the new method allowed for combination drug delivery through an intravenous injection to cross the blood-brain-barrier (BBB).
https://indianexpress.com/article/technology/science/creating-virus-like-particles-for-drug-delivery/
Feb 06, 2016 · Creating virus-like particles for drug delivery; Creating virus-like particles for drug delivery Cells are generally impregnable to most macromolecules. It is this ability to penetrate cells that makes some viruses potentially useful carriers of material.Works For: The Indian Express
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1389-2010&volume=6&issue=1&spage=49
The drug delivery system described here is based on a virus like particle consisting of the recombinant expressed major capsid protein of Polyomavirus, VP1. Polyoma, a murine virus belonging to the Papovaviridae, forms a non-enveloped icosahedral capsid.Author: Christiane Georgens, Jorg Weyermann, Andreas Zimmer
https://www.sciencedirect.com/science/article/pii/S030090841830316X
The major drawback of using virus-like nanoparticles in drug delivery is the particle instability, intrinsic immunogenicity and limitations in antigen fusions. These challenges are addressed by using modified Hepatitis B core protein virus-like particles with enhanced functional properties by removing surface charge, artificial disulfide network introduction and new surface spike region transplantation [ 118 ].Author: Jaison Jeevanandam, Kaushik Pal, Michael K. Danquah
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689521/
Jan 19, 2017 · An alternate type of drug delivery NP that is showing promise is the VLP. 20 VLPs are self‐assembled, homogeneous NPs derived from the coat proteins of viral capsids. They typically lack their natural genome and are therefore noninfectious.Author: Marcus J. Rohovie, Maya Nagasawa, James R. Swartz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193192/
Oct 11, 2011 · Here we describe a safe alternative in which virus-like particles (VLPs), derived from an avian retrovirus, are used to deliver protein to cells. We show that these VLPs are a highly adaptable platform that can be used to deliver proteins either as part of Gag fusion proteins (intracellular delivery) or on the surface of VLPs.Author: Stanislaw J. Kaczmarczyk, Kalavathy Sitaraman, Howard A. Young, Stephen H. Hughes, Deb K. Chatterjee
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
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