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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5,6,7]. The dendrimer architecture has three main sites for drug entrapment by using various mechanisms: (i) void spaces (by molecular entrapment); (ii) branching points (by hydrogen bonding); and (iii) outside surface groups by (charge–charge interactions) ( Figure 1 ).Author: Abhay Singh Chauhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Dendrimers for Drug Delivery and Targeting. The precise control over the distribution of drugs is highly valuable to abolish the typical drawbacks of traditional medicine. Thus, a drug delivery system should be designed to attain the site-specific delivery preferentially.
https://www.sciencedirect.com/topics/chemistry/dendrimer
Dendrimers are attractive macromolecular systems for drug delivery because of their nanometer size range (5–20 nm), ease of preparation and functionalization, and their ability to display multiple copies of surface groups for biological recognition processes (Morgan and Cloninger, 2002). Dendrimer molecules are monodisperse symmetric macromolecules built around a small molecule or in a linear polymer …
https://www.worldofchemicals.com/19/chemistry-articles/dendrimers-for-drug-delivery.html
Dendrimers for drug delivery Abstract Dendrimers are novel and exciting class of highly branched three-dimensional polymer in which growth emanates from a central core molecule such as ammonia , ethylenediamine , and polydiamine or benzene tricarboxylic acid chloride .
https://www.pharmatutor.org/articles/dendrimers-novel-drug-delivery-overview
Dendrimers are being used as drug delivery systems for various drugs like anticancer drugs (methotrexate), drug for prevention of HIV, enhancing bioavailability of pilocarpine for ocular drug delivery. Dendrimers help in achieving increased bioavailability, sustained, controlled as well as targeted release of drug.
https://www.pharmatutor.org/articles/dendrimers-carrier-for-oral-drug-delivery-system
Dendrimers are normally used as carriers for drug delivery especially for oral, ocular and transdermal delivery. Oral drug delivery system are very important to the field of medicine, since most of the common illness are treated via oral route. Encapsulation and conjugation of drug with dendrimers have shown immerse employment for delivery of hydrophobic and labile drugs.
https://pubs.rsc.org/en/content/articlelanding/2014/tb/c4tb00171k#!
Dendrimers for drug delivery - Journal of Materials Chemistry B (RSC Publishing) Due to their nanometric size, dendrimers have been considered as potentially suitable as new vehicles for drug delivery since their infancy. The association of a dendrimer and a drug may occur in different ways, either through covalent or non-covalent interactions.
https://www.sciencedirect.com/science/article/pii/S092849311733103X
Dendrimers, as a type of artificial polymers with unique structural features, have been extensively explored for their applications in biomedical fields, especially in drug delivery. However, one important concern about the most commonly used dendrimers exists - the nondegradability, which may cause side effects induced by the accumulation of synthetic polymers in cells or tissues.Author: Da Huang, Da Huang, Decheng Wu
https://pubs.rsc.org/en/content/articlelanding/2016/bm/c5bm00532a
Dendrimers have shown great promise as carriers in drug delivery due to their unique structures and superior properties. However, the precise control of payload release from a dendrimer matrix still presents a great challenge. Stimuli-responsive dendrimers that release payloads in response to a specific trig Jump to main contentAuthor: Hui Wang, Hui Wang, Quan Huang, Hong Chang, Jianru Xiao, Yiyun Cheng
https://www.sigmaaldrich.com/materials-science/material-science-products.html?TablePage=16375655
Applications of dendrimers Applications highlighted in recent literature include drug delivery, gene transfection, catalysis, energy harvesting, photo activity, molecular weight and size determination, rheology modification, and nanoscale science and technology.
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