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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844929/
Introduction: red blood cells as carriers for drug delivery The optimization of vascular delivery of drugs is an important biomedical problem. This problem is especially acute in case of delivery of potent and specific, yet labile and complex biotherapeutic agents including enzymes, which in most cases require precise localization in the target site.
https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/iub.478
Jul 15, 2011 · A recombinant protein, able to selectively bind a selected drug, is entrapped into red blood cells. The protein‐loaded red blood cells can reversibly bind the drug added ex‐vivo (i.e., before infusion) or in vivo (i.e., after transfusion of the protein‐loaded red cells and the binding of the drug present in circulation).Author: Sara Biagiotti, Maria Filomena Paoletti, Alessandra Fraternale, Luigia Rossi, Mauro Magnani
https://newatlas.com/medical/super-human-red-blood-cells-drug-delivery-mcmaster/
The technique they've developed loads normal red blood cells with synthetic drug molecules to create a powerful hybrid cell designed to deliver drugs to targeted locations in the body.
https://www.nature.com/articles/s41467-018-04791-8
Jun 15, 2018 · RNA delivery for disease treatment often has low uptake efficiencies and cytotoxicity. Here the authors produce extracellular vesicles from red blood cells for in vivo cargo delivery.Author: Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Ch...
https://www.researchgate.net/publication/51499582_Drug_Delivery_by_Red_Blood_Cells
Drug Delivery by Red Blood Cells. Drug delivery is a growing field of interdisciplinary activities that combine the use of new materials with the biochemical properties of selected drugs, with the aim of improving their therapeutic action and reducing their toxicity.
https://www.labroots.com/trending/cell-and-molecular-biology/16638/using-modified-red-blood-cells-drug-delivery-system
Physicists have now created a way to alter red blood cells so they will act as drug delivery systems that can spread therapeutics throughout the body or to specific places. This work, which might apply to the treatment of diseases like Alzheimer's or some types of cancer…
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