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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
Vaccine delivery systems can be classified as follows. Solid particulates: Solid particulate systems such as microspheres and lipospheres are being exploited for vaccine delivery [Table 1] based on the fact that intestine is an imperfect barrier to small particulates. Antigens entrapped in such particulates when taken up by M-cells can generate immunity.
https://www.thno.org/v05p0863.htm
Cell or Cell Membrane-Based Drug Delivery Systems . ... These toxin absorbing RBCm-NPs were applied as a safe vaccine to deliver PFTs to the immune system without any denaturation treatment ... A cellular Trojan horse for delivery of therapeutic nanoparticles into tumors. Nano Lett. 2007;7:3759-65
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-10-3
Jan 07, 2011 · Furthermore, cell-penetrating peptides (CPP) have been known as attractive carrier having applications in drug delivery, gene transfer and DNA vaccination. This review will focus on the utilization of different vaccine delivery systems for prevention or treatment of cancer.Author: Azam Bolhassani, Shima Safaiyan, Sima Rafati
https://pdfs.semanticscholar.org/ecec/f5c1d10334f2e7246be863566ec8d721ba4e.pdf
intradermal, intranasal, tanscutaneous, and needle free delivery. Intradermal delivery includes delivery of vaccine to the dermis or epidermis for enhancement of immunogenicity. Needle free delivery present lowest risk of needle stick injury and transmission of blood borne pathogen through needle and increase compliance. This review represents the different delivery system, characteristics and advancement in the field of vaccine drug delivery.
https://www.frontiersin.org/articles/10.3389/fcimb.2013.00013/full
The most commonly used adjuvants are aluminium based but these can induce local reactions and may fail to generate strong cell-mediated immunity ( Guy, 2007; Harandi et al., 2010 ). As a consequence, there is a great need to develop novel adjuvants and delivery systems for the next generation of vaccines.Author: Anthony E. Gregory, Richard Titball, Diane Williamson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607064/
Mar 25, 2013 · The most commonly used adjuvants are aluminium based but these can induce local reactions and may fail to generate strong cell-mediated immunity (Guy, 2007; Harandi et al., 2010 ). As a consequence, there is a great need to develop novel adjuvants and delivery systems for the next generation of vaccines.Author: Anthony E. Gregory, Richard Titball, Diane Williamson
https://www.sciencedirect.com/science/article/pii/S0264410X14017162
One strategy to improve immunogenicity of T cell epitopes in the absence of adjuvant is the use of delivery systems such as micelles and liposomes that incorporate immunogenic peptides . For example, use of self-assembled peptide amphiphile micelles have shown promise as HIV vaccines , , . Our approach is the production of vaccines composed of long peptides modified with a fluorocarbon chain…Author: James N. Francis, Jean-François Thaburet, Dominique Bonnet, Philip J. Sizer, Carlton B. Brown, Bertr...
https://www.cdc.gov/flu/prevent/how-fluvaccine-made.htm
Sep 24, 2018 · How Influenza (Flu) Vaccines Are Made - CDC. There is a third production technology for flu vaccines that was approved for use in the U.S. market in 2013 and that involves using recombinant technology external icon.Recombinant flu vaccines do not require having a candidate vaccine virus (CVV) sample to produce.
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