We have collected information about Drug And Gene Delivery Nanoparticles for you. Follow the links to find out details on Drug And Gene Delivery Nanoparticles.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667119/
Feb 27, 2009 · To this end, Hanes and coworkers have pioneered the use of MPT as applied to drug and gene delivery applications [10, 115–117], including the transport of nanoparticles in mucus [17, 118, 119]. MPT allows for unparalleled insight into the fractions of particles that are adherent to mucus at any given time, and yields quantitative measures of the extent of particle hindrance to free diffusion at the …Author: Samuel K. Lai, Ying Ying Wang, Justin S Hanes
https://www.sciencedirect.com/science/article/pii/S0169409X12002839
Since the drug/gene is encapsulated in nanoparticles, it is also protected from rapid enzymatic/hydrolytic degradation, an advantage over a free drug/gene in solution. Thus, the nanoparticle-encapsulated therapeutic agents may show greater efficacy through multiple mechanisms such as enhanced tissue/cellular uptake, sustained drug effect, and protection of the therapeutic agent from enzymatic …Author: Jayanth Panyam, Vinod D Labhasetwar
https://www.sciencedirect.com/science/article/pii/S0168365913008079
Nanoparticles made of biodegradable polymers like proteins and polysaccharides can act as efficient drug delivery vehicles for controlled and targeted release, aiming to improve the therapeutic effects and also to reduce the side effects of the formulated drugs.Author: Ahmed O. Elzoghby
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550462/
Iron oxide nanoparticles, otherwise known as magnetic nanoparticles, have been used in biomedical applications for the last 3 decades. However, the potential of magnetic nanoparticles in drug and gene delivery for cancer therapy has only recently been realized. Therapeutic agents are either attached to or encapsulated within the nanoparticle.Author: Narsireddy Amreddy, Anish Babu, Ranganayaki Muralidharan, Janani Panneerselvam, Akhil Srivastava, Re...
https://www.sciencedirect.com/science/article/pii/S2211383517304926
Besides conventional drug delivery, mesoporous silica can also be applied as carrier for gene transfection. It is well known that carriers play an important role in gene delivery, since the naked nucleic acids show little penetration of cell membranes 100. There are two main gene delivery systems, namely viral and non-viral systems.Author: Yixian Zhou, Guilan Quan, Qiaoli Wu, Xiaoxu Zhang, Boyi Niu, Biyuan Wu, Ying Huang, Xin Pan, Chuanbi...
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