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https://extranet.who.int/rhl/topics/preconception-pregnancy-childbirth-and-postpartum-care/pregnancy-complications/preterm-birth/who-recommendation-use-either-dexamethasone-or-betamethasone-antenatal-corticosteroid-choice
Either intramuscular (IM) dexamethasone or IM betamethasone (total 24 mg in divided doses) is recommended as the antenatal corticosteroid of choice when preterm birth is imminent. (Strong recommendation based on low-quality evidence) Publication history. First published: November 2015. Updated: No update planned
https://www.nejm.org/doi/full/10.1056/NEJMoa1516783
In this multicenter, randomized trial involving women at high risk for late preterm delivery, administration of betamethasone significantly reduced the rate of neonatal respiratory complications.Author: Cynthia Gyamfi-Bannerman, Elizabeth A. Thom, Sean C. Blackwell, Alan T N Tita, Uma M. Reddy, George ...
https://clinicaltrials.gov/ct2/show/NCT01697098
Oct 02, 2012 · Dexamethasone for Preterm Labour (PTL) ... The administration of glucocorticoids to accelerate fetal lung maturity in patients with preterm delivery plays an important role for obstetrics and neonatal care. Many studies have shown that maternal administration of glucocorticoids has a significant beneficial effect in decreasing the incidence of ...
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(19)30292-5/fulltext
Nov 01, 2019 · The incidence of survival without neurosensory disability at age 2 years did not differ between dexamethasone and betamethasone treatment. Our findings indicate that either antenatal corticosteroid can be given to women before preterm birth to improve infant and child health.Author: Caroline A Crowther, Caroline A Crowther, Pat Ashwood, Chad C Andersen, Philippa F Middleton, Thach ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307019/
In conclusion, administration of dexamethasone to pregnant women at risk of preterm birth could improve the blood flow in the uterine arteries, fetal MCA, descending aorta and umbilical artery 24 hours after its administration. The valuable effect of its administration is constant regardless of the …Author: Elsnosy Elwany, Shaaban Omar, Abbas Ahmed, Gaber Heba, Darwish Atef
http://www.nrhmorissa.gov.in/writereaddata/Upload/Documents/Antenatal%20Corticosteroids%20in%20Preterm%20Labour(1).pdf
as in true preterm labour and follow the chart. Give one dose of Injection Dexamethasone as described in the box** and prepare for delivery and neonatal resuscitation Give one pre-referral dose of Injection Dexamethasone if the patient is to be referred, otherwise complete the course. Tocolysis (delay of uterine contractions) is to beFile Size: 167KB
https://www.uptodate.com/contents/antenatal-corticosteroid-therapy-for-reduction-of-neonatal-respiratory-morbidity-and-mortality-from-preterm-delivery
{{configCtrl2.info.metaDescription}} INTRODUCTION. In a landmark paper, Liggins and Howie showed that a single course of antenatal corticosteroid therapy administered to women at risk for preterm delivery (PTD) reduced the incidence and severity of respiratory distress syndrome (RDS) and mortality in offspring [].Over two dozen randomized trials have confirmed these findings [].
https://www.medscape.com/viewarticle/533480_9
Nov 06, 2019 · In women at risk for preterm delivery (less than 37 weeks' gestation), antenatal corticosteroids are frequently administered to prevent fetal lung immaturity at birth. Two milliliters of ...
https://www.acog.org/en/Clinical/Clinical%20Guidance/Committee%20Opinion/Articles/2017/08/Antenatal%20Corticosteroid%20Therapy%20for%20Fetal%20Maturation
ABSTRACT: Corticosteroid administration before anticipated preterm birth is one of the most important antenatal therapies available to improve newborn outcomes. A single course of corticosteroids is recommended for pregnant women between 24 0/7 weeks and 33 6/7 weeks of gestation who are at risk of preterm delivery within 7 days, including for those with ruptured membranes and multiple gestations.
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