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https://www.sciencedirect.com/science/article/pii/S1773224716300144
Currently, much importance is given for lipid delivery formulations. Among them, self-emulsifying drug delivery systems (SEDDS) and self-micro emulsifying drug delivery systems (SMEDDS) are important to improve the oral bioavailability of poorly water-soluble drugs , . These delivery systems promote the lymphatic transport of drugs.Author: Venu Madhav Katla, Kishan Veerabrahma
https://www.sciencedirect.com/science/article/pii/S1359644608001463
Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs.Author: Bo Tang, Gang Cheng, Jian-Chun Gu, Cai-Hong Xu
https://www.ncbi.nlm.nih.gov/pubmed/26027464
The present investigations highlight the development of solid self-emulsifying drug delivery system (solid-SEDDS) for improved oral delivery of the poorly water-soluble drug; cilnidipine. Liquid SEDDS of the drug were formulated using Capryol 90 as the oil phase, Tween 80 as the surfactant, and Transcutol HP as the co-surfactant after screening ...Author: Suparna Sacchit Bakhle, Jasmine Gev Avari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241625/
Comparison of pure drug, self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system . From the drug release studies, it can be clearly seen that pure drug released only 40.14% ± 0.19% up to 120 min and SMEDDS and solid-SMEDDS formulation had …
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
drug bioavailability. Self-Emulsifying Drug Delivery Systems (SEDDS) SEDDS are defined as a pre-concentrate containing a mixture of drug, oil, surfactant, co-surfactant and, sometimes, co-solvent [18,26-30]. SEDDS is a broad term associated with the production of emulsions with a droplet size ranging from a few nanometers toFile Size: 540KB
http://ijpsr.com/bft-article/self-emulsifying-drug-delivery-system-a-review/?view=fulltext
SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW HTML Full Text. SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW. Kshitija Khedekar* 1 andSwati Mittal 2 Department of Quality Assurance 1, Department of Pharmaceutics 2, Vivekanand Education Society’s College of Pharmacy, Chembur, Mumbai, Maharashtra, India
https://link.springer.com/article/10.1007%2Fs40005-016-0243-2
Mar 30, 2016 · The optimized SMEDDS formulation was transferred on to the inert adsorbent i.e. Neusilin US2, to formed a solid self emulsifying drug delivery system (S-SMEDDS). Solid SMEDDS with 1:1 ratio (adsorbent: SMEDDS) showed excellent oil adsorption capacity, low …Author: Pankaj V. Dangre, Pankaj V. Dangre, Ritu M. Gilhotra, Shashikant N. Dhole
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
A REVIEW: SELF EMULSIFYING DRUG DELIVERY SYSTEM ... by formulation of the drug in a self‐emulsifying system or alternatively by taking advantage of the natural process of triglyceride digestion. In ... This article describes the development and optimization of a solid ...
https://link.springer.com/article/10.1007/s11095-012-0704-x
Feb 28, 2012 · To develop solid self-emulsifying drug delivery systems (SEDDS) for lipids using poloxamer 188 as both solidifying and emulsifying agents. Mixtures of various lipids with poloxamer 188 and PEG 8000 were prepared at ~75°C. The molten mixtures, with and without dissolved drugs (fenofibrate and probucol), were then cooled to room temperature.Author: Ankita V. Shah, Abu T. M. Serajuddin
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