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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666663/
Recently, cell-penetrating peptides have been proposed to translocate antibodies, proteins, and other molecules in targeted drug delivery. The proposed study presents the synthesis and characterization of a peptide-based chitosan nanoparticle for small interfering RNA (siRNA) delivery, in-vitro.Author: Meenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha, Imen Kahouli, Satya Prakash
https://www.sciencedirect.com/science/article/pii/S0168365906003683
Mean particle size of chitosan–siRNA complexes prepared by simple complexation for both chitosan hydrochloride and glutamate were increased when the concentration of chitosan was increased from 25 to 300 μg/ml in distilled water ().However, a smaller mean particle size of chitosan nanoparticles was obtained when the lower molecular weight of chitosan was used compared to the higher ...Author: Haliza Katas, H. Oya Alpar
https://www.sciencedirect.com/science/article/pii/S0168365913009681
3.2. Formulation and characterization of siRNA loaded chitosan-based nanoparticles 3.2.1. Formulation of the nanoparticles. The rationale for the selection of the excipients to formulate chitosan-based nanoparticles loaded with siRNA was the following.Author: Héloïse Ragelle, Raphaël Riva, G. Vandermeulen, B. Naeye, Vincent Pourcelle, C. S. Le Duff, C. D'Hae...
https://www.hindawi.com/journals/ijbm/2013/146320/
Development of Chitosan Nanoparticles as a Stable Drug Delivery System for Protein/siRNA Haliza Katas , 1 Maria Abdul Ghafoor Raja , 1 and Kai Leong Lam 1 1 Centre for Drug Delivery Research, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, MalaysiaAuthor: Haliza Katas, Maria Abdul Ghafoor Raja, Kai Leong Lam
https://www.researchgate.net/publication/236978255_Development_and_characterization_of_chitosan-PEG-TAT_nanoparticles_for_the_intracellular_delivery_of_siRNA
Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA Article (PDF Available) in International Journal of Nanomedicine 8(default):2041-52 ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910299/
2.2. Synthesis and characterization of siRNA-Npr3 loaded chitosan nanoparticlesThe siRNA-Npr3 loaded chitosan nanoparticles were synthesized by mixing chitosan solution (1 mg/ml chitosan in 0.2 M sodium acetate buffer, pH 4.5) to a mixture containing STPP solution (2.5 mg/ml) and siRNA-Npr3 at 5:1 weight ratio of chitosan to STPP and 50:1 N:P ratio of chitosan and siRNA-Npr3.Author: Balaji Venkatesan, Anusha Tumala, Vimala Subramanian, Elangovan Vellaichamy
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