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https://www.sciencedirect.com/science/article/pii/S0168365901004953
Jan 17, 2002 · Several features have to be considered in the design of targeted polymeric bioconjugates. Fig. 1 shows the typical structure of the targeted polymer–drug conjugates, a structure of targeting moiety and therapeutics attached to a polymer chain. Water-soluble polymers are used as drug carriers to modify the solubility and pharmacokinetics of drugs and to deliver drugs to target sites.Author: Zheng Rong Lu, Jane Guo Shiah, Shinji Sakuma, Pavla Kopečková, Jindřich Kopeček
https://www.researchgate.net/publication/11586305_Design_of_novel_bioconjugates_for_targeted_drug_delivery
Design of novel bioconjugates for targeted drug delivery Article in Journal of Controlled Release 78(1-3):165-73 · February 2002 with 16 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pubmed/11772458
Jan 17, 2002 · Design of novel bioconjugates for targeted drug delivery. Lu ZR(1), Shiah JG, Sakuma S, Kopecková P, Kopecek J. Author information: (1)Department of Pharmaceutics and Pharmaceutical Chemistry/CCCD, University of Utah, Salt Lake City, UT 84112, USA.Author: Zheng Rong Lu, Jane Guo Shiah, Shinji Sakuma, Pavla Kopečková, Jindřich Kopeček
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775858/
Feb 11, 2016 · In this work, novel pD-modified NP-aptamer bioconjugates (Apt-pD-DTX/NPs) were synthesized successfully for the first time, and applied as a targeted drug carrier for breast cancer therapy. By using the facile dopamine polymerization method, CA-PLGA-b-TPGS NPs were simply functionalized by aptamers. The pD film on the surface of NPs could be ...Author: Wei Tao, Xiaowei Zeng, Jun Wu, Xi Zhu, Xinghua Yu, Xudong Zhang, Jinxie Zhang, Gan Liu, Lin Mei
http://www.avantgardemolecular.com/Home.html
Avantgarde Molecular is a biotechnology company developing novel products and technologies at the interface of chemistry and biology. Our goal is to provide innovative and efficient solutions in molecular design, production process and applications, resulting in …
https://www.beilstein-journals.org/bjoc/articles/14/80
On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site Cancer is the second leading cause of death affecting nearly one in two people, and the appearance of new cases is projected to rise by >70% by 2030.
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