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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490019/
Nov 05, 2012 · In summary, we have demonstrated the utility of dendronized AuNPs as a vector for siRNA delivery. In these studies, G2-AuNP suppressed β-gal expression by ~ 50% with minimal toxicity. These nanoparticle vectors possess the benefits of polymeric delivery vehicles such as PEI, while minimizing toxicity through the use of non-toxic core functionality.Author: Sung Tae Kim, Apiwat Chompoosor, Yi-Cheun Yeh, Sarit S. Agasti, David J. Solfiell, Vincent M. Rotell...
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201201141
Dendronized gold nanoparticles (AuNPs) are effective nanocarriers for small interfering RNA (siRNA) delivery. Electrostatic condension of these AuNPs with siRNA provides efficient silencing (∼50%) without cytotoxicity.Author: Sung Tae Kim, Apiwat Chompoosor, Yi-Cheun Yeh, Sarit S. Agasti, David J. Solfiell, Vincent M. Rotell...
https://www.ncbi.nlm.nih.gov/pubmed/22887809
Nov 05, 2012 · Dendronized gold nanoparticles for siRNA delivery. Kim ST(1), Chompoosor A, Yeh YC, Agasti SS, Solfiell DJ, Rotello VM. Author information: (1)Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01003, USA.Author: Sung Tae Kim, Apiwat Chompoosor, Yi-Cheun Yeh, Sarit S. Agasti, David J. Solfiell, Vincent M. Rotell...
https://www.researchgate.net/publication/230658711_Dendronized_Gold_Nanoparticles_for_siRNA_Delivery
Dendronized gold nanoparticles (AuNPs) are effective nanocarriers for small interfering RNA (siRNA) delivery. Electrostatic condension of these AuNPs with siRNA provides efficient silencing (∼50 ...
https://www.sciencedirect.com/science/article/pii/S1525001616306967
Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids. In this review, we focus on the use of covalent and noncovalent gold nanoparticle conjugates for applications in gene delivery and RNA-interference technologies.Author: Ya Ding, Ya Ding, Ziwen Jiang, Krishnendu Saha, Chang Soo Kim, Sung Tae Kim, Ryan F Landis, Vincent ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30696-7
Jun 01, 2014 · Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids. In this review, we focus on the use of covalent and noncovalent gold nanoparticle conjugates for applications in gene delivery and RNA-interference technologies.Author: Ya Ding, Ya Ding, Ziwen Jiang, Krishnendu Saha, Chang Soo Kim, Sung Tae Kim, Ryan F Landis, Vincent ...
https://pubs.acs.org/doi/abs/10.1021/nl9003865
Enhanced Gene Delivery and siRNA Silencing by Gold Nanoparticles Coated with Charge-Reversal Polyelectrolyte. ACS Nano 2010, 4 (9) , 5505-5511. DOI: 10.1021/nn101638u. Hossein Ismaili, Soo Lee, and Mark S. Workentin.Author: Asmaa Elbakry, Alaa Zaky, Renate Liebl, Reinhard Rachel, Achim Goepferich, Miriam Breunig
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