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https://pubs.rsc.org/en/content/articlelanding/2012/sm/c2sm07280g#!
Dendrimer-mediated drug delivery to the skin. Abstract. Nanoparticles have been increasingly used as carriers for local and systemic drug delivery via the skin. Dendrimers are emerging as the new generation of nanocarriers in skin drug delivery mainly due to their small size, extreme molecular uniformity, and highly functional surfaces.
https://www.researchgate.net/publication/255765645_Dendrimer-mediated_drug_delivery_to_the_skin
The role of the follicular route in dendrimer-mediated skin drug delivery. Via particle engineering, dendrimers can be designed to target the hair follicles efficiently; hence the drug loaded in the dendrimers (by encapsulation, complexation or conjugation) can be delivered into the skin.
https://ui.adsabs.harvard.edu/abs/2012SMat....8.4301S/abstract
Not Available adshelp[at]cfa.harvard.edu The ADS is operated by the Smithsonian Astrophysical Observatory under NASA Cooperative Agreement NNX16AC86AAuthor: Mingjing Sun, Aiping Fan, Zheng Wang, Yanjun Zhao
https://www.sciencedirect.com/science/article/pii/S0168365903002001
That is, while only the free drug and not the complex can permeate the skin (because of the molecular weight, hydrophilicity and bulkiness of the latter) the dendrimer functions as a carrier. The carrier transports the drug molecules to the skin surface in a solubilized form from where they partition into stratum corneum, for which they have a greater affinity.Author: Abhay S Chauhan, S Sridevi, Kishore B Chalasani, Akhlesh K Jain, Sanjay K Jain, N.K Jain, Prakash V ...
https://www.dovepress.com/dendrimer-coupled-sonophoresis-mediated-transdermal-drug-delivery-syst-peer-reviewed-fulltext-article-DDDT
It was concluded that dendrimer-coupled sonophoresis-mediated transdermal drug delivery system has the potential to enhance the permeation of DF through the skin. Keywords: sonophoresis, ultrasound, polyamidoamine, permeation enhancers, stratum corneum
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517524/
Dendrimer-coupled sonophoresis-mediated transdermal drug-delivery system for diclofenac. Abstract. The purpose of the present study was to develop a novel transdermal drug-delivery system comprising a polyamidoamine dendrimer coupled with sonophoresis to enhance the permeation of diclofenac (DF) through the skin.Author: Bin Huang, Wei-Jiang Dong, Gao-Yi Yang, Wei Wang, Cong-Hua Ji, Fei-Ni Zhou
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792561/
dendrimer mediated transdermal drug delivery In recent era, transdermal route has rival with oral route as the most flourishing groundbreaking investigation locale in the drug delivery. Skin intrinsic barrier furnish a foremost confront in transdermal drug deliverance.
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