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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995517/
Nov 27, 2019 · 5.4. Brain Drug Delivery with Dendrimer-Based Hybrid Nanoparticles. Marked as synthetic, globular, and monodispersed with spatial arrangement and nanometric macromolecules, dendrimers can be further connected to disparate vehicles for various pharmaceutical and biomedical applications [31,173]. To fathom and settle obstacles in drug delivery ...Author: Yuefei Zhu, Chunying Liu, Zhiqing Pang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Thus, a drug delivery system should be designed to attain the site-specific delivery preferentially. In recent years, improved pharmacokinetics, biodistribution and controlled release of the drug to the specific targeted site has been achieved with polymer based drug delivery.
https://www.sciencedirect.com/science/article/pii/B9780128145272000056
Targeted drug delivery (TDD) means delivering of drugs to a specific site like infected organ, tissue or cell. TDD is important to improve therapeutic efficacy of …Author: Lakshmi Tunki, Hitesh Kulhari, Ramakrishna Sistla, Deep Pooja
https://www.sciencedirect.com/science/article/pii/S2352940718301641
2.3.2. Targeted drug delivery using PAMAM-dendrimer. Targeted drug delivery using nanomaterials such as PAMAM dendrimer bearing ligands has several advantages: (a) it can protect normal cells from cytotoxic agents; (b) it can reduce the dose-dependent side-effects of drugs; (c) it can overcome drug resistance of cancer cells .Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/wnan.1409
Finally, the major challenges that these nanocarriers are currently facing in their clinical translation and possible solutions to address these issues will be discussed, with the aim to provide researchers in the drug delivery field a good understanding of the potential utilities of dendrimer‐based nanocarriers.Author: Hao Jui Hsu, Jason Bugno, Seung Ri Lee, Seungpyo Hong, Seungpyo Hong
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118275238
Jun 15, 2012 · Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights …
https://www.researchgate.net/profile/Mohammad_Najlah/publication/286213900_Dendrimer-Based_Prodrugs_Synthesis_and_Biological_Evaluation/links/5738802108ae9f741b2bcbd1.pdf?origin=publication_list
164 dendrimer-based prodrugs: synthesis and biological evaulation Although coupling of drug molecules to the dendrimer surface is the traditional approach for the preparation of dendrimer prodrugs ...
https://pubs.acs.org/doi/10.1021/mp1000923
The functionalization of pH-sensitiveness and cellular targeting is a promising strategy to fabricate drug delivery systems with high efficiency, high selectivity and low toxicity. In this paper, a poly(l-glutamic acid) dendrimer based drug delivery system with both pH-sensitive and targeting functions is reported.Author: Hui Yuan, Kui Luo, Yusi Lai, Yuji Pu, Bin He, Gang Wang, Yao Wu, Zhongwei Gu
https://www.hindawi.com/journals/jnm/2014/507273/
In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three ...Author: B. Noriega-Luna, Luis A. Godínez, Francisco J. Rodríguez, A. Rodríguez, G. Zaldívar-Lelo de Larrea, ...
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