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https://www.horiba.com/fileadmin/uploads/Scientific/Documents/PSA/Webinar_Slides/AP028.pdf
PLA Nanoparticles for Drug Delivery Targeting ligand provides recognition, enabling targeted nanoparticles to identify and bind to their intended target site. Surface functionalization shields targeted nanoparticles from the immune system. Polymer matrix encapsulates payload molecules in a matrix of biodegradable polymers . Therapeutic payloads include
http://www.nanoparticles.org/pdf/Pun.pdf
Examples of Nanoparticles for Drug Delivery DOXIL Formulation 1. Doxorubicin-containing core 2. Lipid Bilayer membrane 3. PEG-coated surface 4. <100 nm Examples of Nanoparticles for Drug Delivery DOXIL Proposed Mechanism of Action Examples of Nanoparticles for Drug Delivery DOXIL Pharmacokinetics Rats Dogs Gabizon, et al. Pharm Res v10:703 (1993)
https://www.powershow.com/viewht/7aa0f-ZDc1Z/Nanotechnology_Based_Drug_Delivery_powerpoint_ppt_presentation
Mutate chemically labile amino acids to other amino acids, however, antigenicity ... PowerPoint PPT presentation free to view. The Use of Nanoparticles in Drug Delivery Systems - Doxil is the drug doxorubicin HCl encapsulated in an antibody linked PEGylated liposome ...
https://www.slideshare.net/patelbindi/nanoparticle-37752067
Aug 07, 2014 · INTRODUCTION » DEFINITION: » Nanoparticles are subnanosized colloidal drug delivery systems » particle size ranges from 10-1000 nm in diameter. » They are composed of synthetic or semi synthetic polymers carrying drugs or proteinaceous substances, i.e. antigen (s).
https://www.sciencedirect.com/science/article/pii/B9780444626141000077
Drug delivery system (DDS) is one form of drug formulation research to develop innovative formulation and application methods for improving drug specificity by modifying applicable material to a therapeutic agent.Author: Keishiro Tomoda, Kimiko Makino
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.slideshare.net/sagarsavale1/nanoparticulate-drug-delivery-system
May 29, 2016 · 4) Pulmonary drug delivery. Increase adhesiveness of drug to mucosal surface, prolongs the residence time of drug at absorption site. It offers quick onset of action initially and then control release of active moiety which is required by most pulmonary disorders. Budesonide is poorly water soluble corticosteroid has been successfully formulated as a Nanosuspension for pulmonary drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.researchgate.net/topic/Nanoparticles-Drug-Delivery
Mar 09, 2020 · 1) The surface are per amount of drug is increased. This results in faster dissolution rates. In addition, there is more surface energy per amount of material, which encourages aggregation of nanoparticles. Second, the physical properties of the drug can …
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface changes can further enhance the bioactivity of these nanomaterials.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
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