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https://www.amazon.com/Delivery-Protein-Peptide-Drugs-Cancer/dp/1860946275
Written by leading scientists in the field of delivery of protein and peptide drugs to tumors for cancer therapy, this important book provides a broad introduction to the field, with discussion by key experts on the physiological barriers for protein and peptide drugs in tumors, and the different approaches to stabilization of these drugs in biological surroundings, as well as their enhanced delivery to tumors and inside cancer …Author: Vladimir P. Torchilin
https://www.sciencedirect.com/science/article/pii/S0169409X04002686
The direct intracellular delivery of proteins, or active peptide domains, has, until recently, been difficult to achieve due primarily to the bioavailability barrier of the plasma membrane, which effectively prevents the uptake of macromolecules by limiting their passive entry.Author: Jehangir S. Wadia, Steven F. Dowdy
https://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00750
Protein/peptide drugs possess unique advantages, such as high pharmacological potency, molecular specificity, multifunctionality, and low toxicity, and thus hold great potential for use in cancer therapy. In the past decades, great achievements have been made in protein delivery systems, which can protect cargo proteins against detrimental physiological environments and efficiently deliver ...Author: Xun Liu, Fan Wu, Yong Ji, Lichen Yin
https://www.ncbi.nlm.nih.gov/pubmed/30428665
Feb 20, 2019 · Recent Advances in Anti-cancer Protein/Peptide Delivery. Liu X(1), Wu F(1), Ji Y(2), Yin L(1). Author information: (1)Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology , Soochow University , Suzhou 215123 , China.Author: Xun Liu, Fan Wu, Yong Ji, Lichen Yin
https://www.worldscientific.com/doi/abs/10.1142/9781860948039_0004
Basic Strategies for PEGylation of Peptide and Protein Drugs. Gianfranco Pasut, Margherita Morpurgo; ... Delivery of Protein and Peptide Drugs in Cancer. Enhanced Permeability and Retention (EPR) Effect and Tumor-Selective Delivery of Anticancer Drugs ... PEGylated Proteins in Immunotherapy of Cancer. James F. Eliason; Delivery of Protein and ...
https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
Nov 09, 2012 · TMAs have mostly been used as naked antibodies but there is now high expectation of their employment in Targeted Drug Delivery (TDD), mainly because TDD systems can overcome many of the non-specific side effects associated with traditional cancer chemotherapy [5].Author: Michael A Firer, Gary Gellerman
https://drug-dev.com/peptide-based-cancer-therapeutics/
Discovery of several protein/peptide receptors and tumor-related peptides and proteins is expected to create a new wave of more effective and selective anti-cancer drugs in the future, capturing the large share of the cancer therapeutic market.
https://phys.org/news/2018-01-biologists-peptide-cancers.html
Jan 16, 2018 · MIT biologists have designed a new peptide that can disrupt a key protein that many types of cancers, including some forms of lymphoma, leukemia, and breast cancer, need to survive.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539351/
Dec 20, 2012 · BN/GRP (bombesin/gastrin-releasing peptide) peptides were shown to bind selectively to the G-protein-coupled receptors on the cell surface, stimulating the growth of various malignancies in murine and human cancer models [134, 135]. Thus, it has been proposed that the secretion of BN/GRP by neuroendocrine cells might be responsible for the development and progression of prostate cancer …Author: Jyothi Thundimadathil
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-017-0328-x
Mar 21, 2017 · ELP also enhanced the delivery of ELP-conjugated therapeutic peptides, which inhibited the attachment, spreading, migration and invasion of human ovarian cancer cells in cell culture and also inhibited the metastasis of ovarian cancer cells in vivo .Author: Susan Marqus, Elena Pirogova, Terrence J. Piva
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