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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698461/
Delivery of small-interfering RNA (siRNA) to the brain Saroj P Mathupala , PhD Wayne State University School of Medicine, Karmanos Cancer Institute, Department of Neurological Surgery, 607 HWCRC, 4100 John R Road, MI 48201, Detroit, USA Tel: +1 313 576 8352; Fax: +1 313 576 8342; E-mail: ude.enyaw.dem@alapuhtamsAuthor: Saroj P Mathupala
http://www.nature.com/articles/nbt1101
May 22, 2005 · Delivery of small interfering RNAs (siRNAs) into cells is a key obstacle to their therapeutic application. We designed a protamine-antibody fusion protein to deliver siRNA …Author: Erwei Song, Pengcheng Zhu, Sang Kyung Lee, Dipanjan Chowdhury, Steven Kussman, Derek M Dykxhoorn, Yi...
https://advances.sciencemag.org/content/5/9/eaaw6499.full
Sep 01, 2019 · In the present study, we showed that natural halloysite nanotube (HNT)–assisted delivery of an active small interfering RNA (siRNA) targeting receptor-interacting protein kinase 4 ( RIPK4 ) efficiently silenced its expression to treat bladder cancer.Author: Jianye Liu, Yi Zhang, Qinghai Zeng, Hongliang Zeng, Xiaoming Liu, Pei Wu, Hongyi Xie, Leye He, Zhi L...
https://pubs.rsc.org/en/content/articlelanding/2019/nr/c9nr06303j
Small interfering RNA (siRNA) is a promising tool for the treatment of skin disorders including skin squamous cell carcinoma (SCC). This article develops a topical formulation for the transdermal delivery of siRNA. The formulation is built on mesoporous silica nanoparticles (MSNPs) with a loading capacity of Jump to main contentAuthor: Daniel Chin Shiuan Lio, Chenghao Liu, Myo Myo Swe Oo, Christian Wiraja, Melissa Hui Yen Teo, Mengjia...
https://www.ncbi.nlm.nih.gov/pubmed/29803999
Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression. Wang B(1), Ding Y(2), Zhao X(3), Han X(3), Yang N(4), Zhang Y(5), Zhao Y(3), Zhao X(4), Taleb M(3), Miao QR(6), Nie G(7).Author: Bin Wang, Bin Wang, Yanping Ding, Yanping Ding, Xiaozheng Zhao, Xiaozheng Zhao, Xuexiang Han, Xuexia...
https://www.sciencedirect.com/science/article/pii/S0142961218303764
Nanocarriers including liposomes, polymer-based vehicles and peptide self-assemblies have been widely used for delivery of gene therapeutics in vivo [ [22], [23], [24]]. A desirable nanocarrier for small interfering RNAs (siRNAs) is supposed to protect siRNAs from degradation in circulatory system,...Author: Bin Wang, Bin Wang, Yanping Ding, Yanping Ding, Xiaozheng Zhao, Xiaozheng Zhao, Xuexiang Han, Xuexia...
https://onlinelibrary.wiley.com/doi/10.1002/adma.201600554
May 11, 2016 · Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy Ran Zhang National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190 P. R. ChinaAuthor: Ran Zhang, Ran Zhang, Yan Li, Bingbing Hu, Zhiguo Lu, Jinchao Zhang, Xin Zhang
https://www.nature.com/articles/nature05901
Jun 17, 2007 · A major impediment in the treatment of neurological diseases is the presence of the blood–brain barrier, which precludes the entry of therapeutic molecules from blood to brain. Here we show that a short peptide derived from rabies virus glycoprotein (RVG) enables the transvascular delivery of small interfering RNA (siRNA) to the brain.Author: Priti Kumar, Haoquan Wu, Jodi L. McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L. Davidson, Sang K...
https://www.exosome-rna.com/delivery-of-small-interfering-rnas-to-cells-via-exosomes/
Oct 21, 2015 · Delivery of Small Interfering RNAs to Cells via Exosomes Posted by: Exosome RNA Administrator in Methods October 21, 2015 0 6,152 Views Exosomes are small membrane bound vesicles between 30 and 100 nm in diameter of endocytic origin that are secreted into the extracellular environment by many different cell types.
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