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https://www.researchgate.net/publication/8694837_Polymeric_Micelles_for_Delivery_of_Poorly_Water-Soluble_Compounds
We summarize the development and evaluation of new type of phospholipid polymers as a solubilizer for poorly water-soluble compounds. That is, a water-soluble and amphiphilic poly(2 ...
https://www.researchgate.net/publication/40034606_Recent_advances_in_intravenous_delivery_of_poorly_water-soluble_compounds
Recent advances in intravenous delivery of poorly water-soluble compounds Article · Literature Review in Expert Opinion on Drug Delivery 6(12):1261-82 · December 2009 with 79 Reads
https://www.sciencedirect.com/science/article/abs/pii/S0009308412000084
Lipospheres and pro-nano lipospheres for delivery of poorly water soluble compounds. ... Lipospheres are a drug encapsulation system composed of water dispersible solid microparticles of particle size between 0.01 and 100 μm in diameter with a solid hydrophobic lipid core stabilized by a layer of phospholipid molecules embedded in their ...Author: Anna Elgart, Irina Cherniakov, Yanir Aldouby, Abraham J. Domb, Amnon Hoffman
https://www.ncbi.nlm.nih.gov/pubmed/19941409
Recent advances in intravenous delivery of poorly water-soluble compounds. Shi Y(1), Porter W, Merdan T, Li LC. Author information: (1)Department R43D, Abbott Laboratories, 100 Abbott Park Rd, Abbott Park, IL 60064-6196, USA.Author: Yi Shi, William Porter, Thomas Merdan, Luk Chiu Li
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629443/
Aug 24, 2015 · Liposomal drug delivery offer significant therapeutic benefits to poorly soluble compounds. One such example is the formulation of cyclosporine and paclitaxel in which surfactants and organic co-solvents are used for systemic administration in humans. These solubilizers may cause toxicity at the administered doses.Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.sciencedirect.com/science/article/pii/S0009308412000084
Herein, we have reviewed several existing and potential applications for lipospheres and PNL. In oral delivery, highly lipophilic and poorly water soluble compounds that also undergo extensive presystemic intestinal metabolism are the ultimate candidates for incorporation into lipospheres to obtain increased and less variable bioavailability.Author: Anna Elgart, Irina Cherniakov, Yanir Aldouby, Abraham J. Domb, Amnon Hoffman
https://www.apv-mainz.de/fileadmin/dateiablage/apv-mainz/Seminare/oeffentllich/6807_poorly_soluble.pdf
number of biological compounds (New Biological Entities), but also more and more poorly soluble small molecules (New Chemical En-tities) arrive at the formulator‘s lab bench. Half a day is scheduled to introduce you to the options of formulation development for parenteral drug candidates, which are poorly water soluble. An
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