Delivery Of Poorly Water Soluble Compounds

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Polymeric Micelles for Delivery of Poorly Water-Soluble ...

    https://www.researchgate.net/publication/8694837_Polymeric_Micelles_for_Delivery_of_Poorly_Water-Soluble_Compounds
    We summarize the development and evaluation of new type of phospholipid polymers as a solubilizer for poorly water-soluble compounds. That is, a water-soluble and amphiphilic poly(2 ...

Recent advances in intravenous delivery of poorly water ...

    https://www.researchgate.net/publication/40034606_Recent_advances_in_intravenous_delivery_of_poorly_water-soluble_compounds
    Recent advances in intravenous delivery of poorly water-soluble compounds Article · Literature Review in Expert Opinion on Drug Delivery 6(12):1261-82 · December 2009 with 79 Reads

Lipospheres and pro-nano lipospheres for delivery of ...

    https://www.sciencedirect.com/science/article/abs/pii/S0009308412000084
    Lipospheres and pro-nano lipospheres for delivery of poorly water soluble compounds. ... Lipospheres are a drug encapsulation system composed of water dispersible solid microparticles of particle size between 0.01 and 100 μm in diameter with a solid hydrophobic lipid core stabilized by a layer of phospholipid molecules embedded in their ...Author: Anna Elgart, Irina Cherniakov, Yanir Aldouby, Abraham J. Domb, Amnon Hoffman

Recent advances in intravenous delivery of poorly water ...

    https://www.ncbi.nlm.nih.gov/pubmed/19941409
    Recent advances in intravenous delivery of poorly water-soluble compounds. Shi Y(1), Porter W, Merdan T, Li LC. Author information: (1)Department R43D, Abbott Laboratories, 100 Abbott Park Rd, Abbott Park, IL 60064-6196, USA.Author: Yi Shi, William Porter, Thomas Merdan, Luk Chiu Li

Insoluble drug delivery strategies: review of recent ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629443/
    Aug 24, 2015 · Liposomal drug delivery offer significant therapeutic benefits to poorly soluble compounds. One such example is the formulation of cyclosporine and paclitaxel in which surfactants and organic co-solvents are used for systemic administration in humans. These solubilizers may cause toxicity at the administered doses.Author: Sandeep Kalepu, Vijaykumar Nekkanti

Lipospheres and pro-nano lipospheres for delivery of ...

    https://www.sciencedirect.com/science/article/pii/S0009308412000084
    Herein, we have reviewed several existing and potential applications for lipospheres and PNL. In oral delivery, highly lipophilic and poorly water soluble compounds that also undergo extensive presystemic intestinal metabolism are the ultimate candidates for incorporation into lipospheres to obtain increased and less variable bioavailability.Author: Anna Elgart, Irina Cherniakov, Yanir Aldouby, Abraham J. Domb, Amnon Hoffman

Oral and Parenteral Delivery of Poorly Soluble Compounds ...

    https://www.apv-mainz.de/fileadmin/dateiablage/apv-mainz/Seminare/oeffentllich/6807_poorly_soluble.pdf
    number of biological compounds (New Biological Entities), but also more and more poorly soluble small molecules (New Chemical En-tities) arrive at the formulator‘s lab bench. Half a day is scheduled to introduce you to the options of formulation development for parenteral drug candidates, which are poorly water soluble. An

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