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https://www.researchgate.net/publication/224938294_Delivery_of_Neurotherapeutics_Across_the_Blood_Brain_Barrier_in_Stroke
Delivery of Neurotherapeutics Across the Blood Brain Barrier in Stroke Article · Literature Review (PDF Available) in Current Pharmaceutical Design 18(25):3704-20 · May 2012 with 149 Reads
http://www.eurekaselect.com/101026/article
Keywords:Cell penetrating peptide, TAT protein transduction domains, blood brain barrier, stroke, neuroprotection, brain cells, central nervous system (CNS), drug delivery, neurotherapeutics, ischemic brain injury. Abstract:Stroke is a devastating disease with few therapeutic options. Despite our growing understanding of the critical ...
https://www.ingentaconnect.com/content/ben/cpd/2012/00000018/00000025/art00012
Delivery of Neurotherapeutics Across the Blood Brain Barrier in Stroke Buy Article: $68 ... show great potential to deliver neurotherapeutics across the BBB for the treatment of ischemic brain injury. This review begins with a brief introduction to the BBB in relation to drug delivery and then provides an overview of the development of drug ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539316/
INTRODUCTION. The blood-brain barrier (BBB) is the bottleneck in brain drug development and is the single most important factor limiting the future growth of neurotherapeutics. 1 The BBB problem is illustrated in Figure 1, which is a whole body autoradiogram of a mouse sacrificed 30 min after intravenous injection of radiolabeled histamine, a small molecule of only ∼100 Da in molecular mass.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077137/
Oct 18, 2016 · How to circumvent the blood–brain barrier? Based on better knowledge of BBB biology, several different strategies for delivering molecules across the barrier have been developed for treating CNS diseases, and can be broadly classified as invasive, pharmacological, and physiological approaches.15–19 The invasive method is based on direct delivery of drugs into the brain tissue …Author: Débora B Vieira, Lionel F Gamarra
https://www.transbarrier.com/about/
TransBarrier® specializes in helping individuals recover from stroke, even if severe, using its innovative, patented TransBarrier® drug delivery method.TransBarrier’s patented treatment is designed to enhance the selective delivery of drugs across the blood-brain barrier. For further specific information regarding types of treatment responses, please click here.
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