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https://www.sciencedirect.com/science/article/pii/S0009250917307509
Although the structure seems simple, polymeric Janus particles have great potential for drug delivery applications. The unique structure enables the hemispheres of each individual particle to contain a different active pharmaceutical ingredient (API), or different concentrations of a release-controlling polymer to create a two stage release profile for an API present in both hemispheres.Author: Pavithra Sundararajan, Jianbin Wang, Lawrence A. Rosen, Adam Procopio, Kenneth Rosenberg
https://blogs.iu.edu/sciu/2017/12/05/two-faced-particles/
Dec 05, 2017 · A study from this year has shown that a Janus particle — a double-sided nanosphere named after the two-faced Roman God Janus — can split the two jobs between the two sides. Janus particles are a few hundred times thinner than the thickness of your fingernail, so it’s not surprising that they are difficult to make.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711559/
Aug 23, 2019 · For this reason, Janus particles have found applications in increasing number of nanomedicine areas, from dual-release drug delivery, to theranostics, and biosensing. This is particularly true in the last five years when many more Janus particles were tested in vitro and in vivo, providing large amount of valuable information regarding their behavior in biological systems.Author: Tu C Le, Jiali Zhai, Wei-Hsun Chiu, Phong A Tran, Nhiem Tran
https://www.dovepress.com/janus-particles-recent-advances-in-the-biomedical-applications-peer-reviewed-fulltext-article-IJN
Janus particles, among many NPs systems, have received considerable amount of interest recently as the next-generation “smart” nanomaterials due to their complexity and flexibility in structures and properties with a wide range of potential applications in drug delivery, imaging, bio-sensing, and theranostics. 13–15 Janus particles, named after the two-faced roman god-Janus, are used to describe a unique class of particles …Author: Tu C Le, Jiali Zhai, Wei-Hsun Chiu, Phong A Tran, Nhiem Tran
https://www.aiche.org/conferences/aiche-annual-meeting/2012/proceeding/paper/692e-engineered-biodegradable-janus-particles-drug-delivery
Nov 01, 2012 · (692e) Engineered Biodegradable Janus Particles for Drug Delivery. Authors: Recent advances in the field of nanotechnology have generated interest in the creation of “Janus” particles, whose dual surface chemistries and unique properties set them apart from spherical isotropic particles.
https://www.researchgate.net/publication/267308915_337461_Biodegradable_Janus_Particles_for_Drug_Delivery_Bi-Compartmental_Encapsulation_of_Two_API_of_Disparate_Solubility
Janus particles have unique chemical, optical, electrical, and physical properties that set them apart from their isotropic counterparts. Janus particles hold great promise as tiny colloidal...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582348/
Mar 06, 2012 · With its unique structure of two compartments, Janus particles inadequate, including to be used as a drug delivery system to deliver multiple payloads with widely different solubility.Author: Hui Xie, Zhi-Gang She, Si Wang, Gaurav Sharma, Jeffrey W. Smith
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