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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
Yousef Javadzadeh, Shadi Yaqoubi, in Nanostructures for Drug Delivery, 2017. Abstract. Pulmonary drug delivery has attracted tremendous interest in the past two decades. In order to get both local and systemic effects, lungs as the main part of the respiratory system offer an interesting route to noninvasive drug administration.
https://www.pharmatutor.org/articles/pulmonary-drug-delivery-a-review
Drugs like sodium carmoglicate are absorbed to less extent when given orally. And some other drugs like isoprenaline is metabolized in the liver. These types of drugs can be administered through pulmonary route. Pulmonary route have been used to treat various respiratory diseases for centuries.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Pulmonary drug delivery strategies: A concise, systematic review ... treatment of various chronic diseases a growing attention has been given to the development of targeted drug delivery systems. Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung ...
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how—with the right knowledge and expertise—these …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884307/
Apr 19, 2002 · With more emphasis on the lung as a route of administration, physicians, pharmacists and other health professionals will need to have a basic understanding of the science behind pulmonary drug delivery. Part I of this review on pulmonary drug delivery addresses the physiological factors affecting therapeutic effectiveness of inhaled drug ...Author: N. R. Labiris, M. B. Dolovich
https://www.gilberttechnologies.eu/pulmonary-administration-route/
Pulmonary administration route. In the treatment of lung diseases and the treatment of certain other diseases inhalation therapy is a very frequently applied method to administer pharmaceuticals. The advantages of direct local administration into the lungs are most convincing: In the treatment of lung diseases and the treatment of certain other ...
https://www.atsjournals.org/doi/full/10.1513/pats.200409-049TA
Dec 01, 2004 · No noninvasive route of drug delivery provides the bioavailability of the pulmonary epithelium. The lungs are far more permeable to macromolecules than any other portal of entry into the body ().Some of the most promising therapeutic agents are peptides and proteins, which could be inhaled instead of injected, thereby improving compliance.Author: John S. Patton, C. Simone Fishburn, Jeffry G. Weers
https://pdfs.semanticscholar.org/803f/9880ca4eff1e1a0c60f790657d3f412f1513.pdf
Techniques Used for Drug Administration by Pulmonary Route Two techniques can be used for administration of drugs by pulmonary route: aerosol inhalation (which is used in intranasal administration) and intratracheal instillation. Intratracheal administration is a simple, non-expensive process, but the distribution of PULMONARY
http://www.pharmtech.com/pulmonary-drug-delivery-particle-engineering-inhaled-therapeutics
Feb 02, 2014 · The pulmonary route is gaining increasing popularity as a fast and effective way of delivering drugs to the lungs both locally and systemically. There are several reasons for this interest, noted Conrad Winters, PhD, director, and Filipe Neves, PhD, group leader, both from the Drug Product Development Group at Hovione.
https://www.sciencedirect.com/topics/chemistry/pulmonary-drug-delivery
Furthermore, the delivery of atropine sulphate nanoparticles as an antidote for organophosphorus poisoning with better bioavailability has been investigated. Therefore, research reveals that there is a growing interest in pulmonary delivery of various drugs for the management of systemic disorders. 4.2.1 Limiting factors for pulmonary delivery
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