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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086417/
4. Challenges in Topical Delivery. The greatest challenge for dermal penetration is the tough horny layer, that is, stratum corneum (SC), the uppermost layer of the skin, which is the rate limiting step for epidermal drug transport [].The physicochemical factors of drug like log P, pK a, solubility, and molecular mass also play an important role in the selection of components for the topical ...Author: Kaisar Raza, Manish Kumar, Pramod Kumar, Ruchi Malik, Gajanand Sharma, Manmeet Kaur, O. P. Katare
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116302/
These flexible vesicles may become a promising carrier for the transdermal delivery of aceclofenac. It helps in reducing the dose of drug applied topically. The data presented here suggest the possibility of substituting systemic treatment of osteoarthritis and rheumatoid arthritis with local treatment.
https://www.hindawi.com/journals/bmri/2014/406731/
4. Challenges in Topical Delivery. The greatest challenge for dermal penetration is the tough horny layer, that is, stratum corneum (SC), the uppermost layer of the skin, which is the rate limiting step for epidermal drug transport [].The physicochemical factors of drug like log , pK a, solubility, and molecular mass also play an important role in the selection of components for the topical ...Author: Kaisar Raza, Manish Kumar, Pramod Kumar, Ruchi Malik, Gajanand Sharma, Manmeet Kaur, O. P. Katare
https://www.sciencedirect.com/science/article/pii/S0378517312008447
Nov 15, 2012 · Electrospun zein/eudragit nanofibers based dual drug delivery system for the simultaneous delivery of aceclofenac and pantoprazole. Author links open overlay panel K. Karthikeyan a Soma Guhathakarta b Rama Rajaram a Purna Sai Korrapati a. Show more.Author: K. Karthikeyan, Soma Guhathakarta, Rama Rajaram, Purna Sai Korrapati
https://www.researchgate.net/publication/261513942_Topical_Delivery_of_Aceclofenac_Challenges_and_Promises_of_Novel_Drug_Delivery_Systems
Topical Delivery of Aceclofenac: Challenges and Promises of Novel Drug Delivery Systems Kaisar Raza, 1 Manish Kumar, 1 Pramod Kumar, 1 Ruchi Malik, 1 Gajanand Sharma, 2
https://www.researchgate.net/publication/51240152_Preparation_and_Characterization_of_Ethosomes_for_Topical_delivery_of_Aceclofenac
Preparation and Characterization of Ethosomes for Topical delivery of Aceclofenac Article (PDF Available) in Indian Journal of Pharmaceutical Sciences 72(5):582-6 · September 2010 with 620 Reads
https://www.ijper.org/sites/default/files/IndJPhaEdRes_52_4_581_0.pdf
Preparation and evaluation of aceclofenac loaded NLC gel.10,11 The suitable NLC formulation for the topical delivery of aceclofenac was selected based on the evaluation characteristics like: particle size, entrapment efficiency and in vitro release. It was found that the formulation F 1 is more suitable among the other formulations.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/aceclofenac
Among the nanosized colloidal dispersions used for transdermal delivery of aceclofenac (Table 8.2), the following two types will be discussed in more detail: microemulsions as thermodynamically stable, and nanoemulsions as kinetically stable systems (McClements, 2012).Our group has assessed both types as prospective carriers for aceclofenac.
https://onlinelibrary.wiley.com/doi/10.1002/adv.21482
Microcapsules of aceclofenac with pH‐dependent release properties for achieving targeted delivery to colon were developed. A solvent evaporation technique was adopted for microcapsules preparation using Eudragit RS 100 as a retardant polymer.Author: Muhammad Farooq, Mahmood Ahmad, Asadullah Madni, Muhammad Hanif, Muhammad Rizwan Khan
http://ijpsr.com/bft-article/design-and-characterization-of-press-coated-tablets-of-aceclofenac-for-pulsatile-delivery/?view=fulltext
ABSTRACT: An oral press-coated tablet was developed by means of direct compression to achieve the time-controlled disintegrating or rupturing function with a distinct predetermined lag time. The aim of the present study is to develop time depended drug delivery systems for Aceclofenac by using HPMC K100M and ethylcellulose (EC) as coating material.
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