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https://www.selleckchem.com/products/ABT-751.html
34 rows · ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.Brand: Selleck Chemicals
https://www.tocris.com/products/abt-751_4138
Hande et al (2006) The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: results of a phase 1 study. Clin.Cancer Res. 12 2834 PMID: 16675578 If you know of a relevant reference for ABT 751, please let us know.Brand: Tocris Bioscience
http://www.abmole.com/products/abt-751.html
ABT-751 is an orally bioavailable tubulin inhibitor with IC50 of about 1.5 and 3.4 µM in neuroblastoma and non-neuroblastoma cell lines, respectively. Buy Microtubule inhibitor ABT-751 …
https://www.medchemexpress.com/ABT-751.html
ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively. - Mechanism of Action & Protocol.Brand: Medchemexpress
https://www.ncbi.nlm.nih.gov/pubmed/19398903
A single dose of ABT-751 (30 mg/kg, intravenously) induced a rapid, transient reduction in tumor perfusion. After 1 h, tumor perfusion decreased by 57% before recovering to near pretreatment levels within 6 h. In contrast, ABT-751 produced little change in muscle perfusion at either time point.Author: Yanping Luo, Vincent P. Hradil, David J. Frost, Saul H. Rosenberg, Gary B. Gordon, Sherry J. Morgan,...
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