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https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(08)00069-6
Mar 06, 2008 · A variety of materials for cell delivery are under development, and these materials must typically function to deliver the cells in a minimally invasive manner, allow for delivery of single or mixed cell populations, and cue transplanted cells to organize into …Author: David J. Mooney, Herman Vandenburgh, Herman Vandenburgh
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(08)00069-6?scriptOff=true&code=cell-site
Many cell populations, derived from both adult tissues and embryonic stem cells, show promise for the treatment of a variety of diseases. Although the major effort in stem cell therapies in the past has been identifying potentially therapeutic cells, it is now clear that developing systems to deliver these cells and promote their efficient engraftment will provide an equally challenging task ...Author: David J. Mooney, Herman Vandenburgh, Herman Vandenburgh
https://www.sciencedirect.com/science/article/pii/S1934590908000696
Mar 06, 2008 · A variety of materials for cell delivery are under development, and these materials must typically function to deliver the cells in a minimally invasive manner, allow for delivery of single or mixed cell populations, and cue transplanted cells to organize into …Author: David J. Mooney, Herman Vandenburgh, Herman Vandenburgh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763210/
Aug 22, 2018 · Cargo delivery mechanism versus scale of throughput for nano- and micro-mechanical membrane disruption techniques. For injection mechanisms, the nano or micro-mechanical element is hollow, thus allowing injection of cargo. Dissociation-based delivery works by enabling cargo to detach from the penetrating element once inside the cell.Author: Martin P. Stewart, Martin P. Stewart, Robert Langer, Klavs F. Jensen
https://www.cell.com/cell-stem-cell/pdf/S1934-5909(08)00069-6.pdf
Cell Stem Cell Review Cell Delivery Mechanisms for Tissue Repair David J. Mooney1,* and Herman Vandenburgh1,2 1School of Engineering and Applied Sciences, Harvard University, 29 Oxford Street, Pierce Hall, Room 325, Cambridge, MA 02138, USA 2Department of Pathology, Brown Medical School, Providence, RI 02906, USA *Correspondence: [email protected] ...
https://www.pnas.org/content/110/6/2082
Feb 05, 2013 · A mixture of cells and the desired delivery material is then placed into the inlet reservoir and Teflon tubing is attached at the inlet. A pressure regulator is then used to adjust the pressure at the inlet reservoir and drive the cells through the device. Treated cells are …Author: Armon Sharei, Janet Zoldan, Andrea Adamo, Woo Young Sim, Nahyun Cho, Emily Jackson, Shirley Mao, Sab...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345138/
Eukaryotes have evolved elaborate vesicular trafficking mechanisms that accomplish this feat by ensuring (i) proper macromolecule sorting and delivery to, or retention within, the appropriate destination, and (ii) proper maturation of secretory and endocytic organelles . These basic mechanisms are conserved among all eukaryotic cell types.Author: Anand Sitaram, Michael S. Marks
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891846/
Dec 28, 2013 · Dendrimers are capable of binding miRNA and aiding in the entry into cells, but the entry is non-specific in nature. The alternate mechanism of cell entry that should not be overlooked as this has the potential to protect miRNA by avoiding the endosomal and lysosomal compartments .Author: Yu Zhang, Zaijie Wang, Richard A. Gemeinhart
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009470/
Another novel approach is to apply cell-based delivery mechanisms to deliver miRNA mimics and miRNA antagonists for cancer therapies. For example, neural stem cells and mesenchymal stem cells can serve as drug carriers targeting GBM [ 148 ].Author: Yunching Chen, Dong Yu Gao, Leaf Huang
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