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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as tools to enable these strategies. These include benefits such as their small size which allows penetration of cell membranes,...Author: Wim H De Jong, Paul Ja Borm
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://manufacturingchemist.com/news/article_page/Nanoparticles_an_effective_means_of_drug_delivery/106763
For marketed products requiring lifecycle extension opportunities, nanoparticle formulation strategies provide a means to develop a new drug delivery platform with improved therapeutic outcome incorporating the existing drug, thus creating new avenues for addressing unmet medical needs.
https://drug-dev.com/nanoparticles-a-revolution-in-the-development-of-drug-delivery-vehicles/
Nanoparticles comprised of polymers or lipids can be used to encapsulate biological or small molecule active pharmaceutical ingredients (APIs) for drug delivery. A major advantage of this approach is that it protects the API from harsh extracellular environmental conditions in vivo , allowing delivery of the intact API into the target tissues, cells, and sub-cellular compartments.
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Researchers are developing nanoparticles that can delivery drugs across the brain barrier to tackle neurologic disorders. A method being developed to fight aging uses mesoporous nanoparticles with a coating that releases the contents of the nanoparticle when an emzyme found in aging cells is present.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.annualreviews.org/doi/abs/10.1146/annurev-med-040210-162544
Nanomedicine, the application of nanotechnology to medicine, enabled the development of nanoparticle therapeutic carriers. These drug carriers are passively targeted to tumors through the enhanced permeability and retention effect, so they are ideally suited for the delivery of chemotherapeutics in cancer treatment. Indeed, advances in nanomedicine have rapidly translated into clinical ...Author: Andrew Andrew Wang, Robert Langer, Omid C. Farokhzad
https://www.sciencedirect.com/science/article/pii/S1319016411000302
Nanoparticles (NP) are a type of colloidal drug delivery system comprising particles with a size range from 10 to 1000 nm in diameter. Nanoparticles may or may not exhibit size-related properties that differ significantly from those observed in fine particles or bulk materials ( Buzea et al., 2007 ).Author: Sagar R. Mudshinge, Amol B. Deore, Sachin Patil, Chetan M. Bhalgat
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