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https://www.neuromodulation.com/pump
In intrathecal drug delivery, pain medications and/or medications used for spasticity are introduced directly to the spinal fluid (intrathecal space) through a drug delivery system comprised of a pump and catheter. The intrathecal space is usually accessed from the lumbar region of the lower back.
https://www.ucsfhealth.org/treatments/intrathecal-drug-delivery
Intrathecal drug delivery is used to treat pain from a variety of conditions, such as chronic back and neck pain, sciatica, chronic abdominal pain, failed back and neck surgery, cancer and reflex sympathetic dystrophy or complex regional pain syndrome.
https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
Pain relief through spinal drug delivery systems, also called intrathecal drug delivery systems, involves implanting a small pump or using a catheter that delivers medication directly to the spinal cord, where pain signals travel. In many cases, spinal drug delivery systems are used to treat people who have cancer pain.
https://www.neuromodulation.com/fact_sheet_intrathecal_drug_delivery
Intrathecal drug delivery systems are implanted pumps that target pain relief or anti-spasm medication to an area of the spine that relays signals between an affected area of the body and the brain. Persons with chronic pain or muscle spasms may be considered for such a device if, over time,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227625/
Nov 06, 2014 · Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery.
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Intrathecal (IT) administration, i.e., the injection of substances directly into cerebrospinal fluid (CSF) that fills the thecal sac, is a potentially powerful drug delivery approach. This route of administration can achieve a high concentration of therapeutic agent within the central nervous system (CNS) while minimizing off-target exposure and associated toxicity [ 1 ].Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
http://www.britishpainsociety.org/static/uploads/resources/files/itdd_2015_pro_v3.pdf
Delivery of the drug by the intrathecal (spinal) route is a means of achieving enhanced therapeutic effects. The smaller doses needed for intrathecal administration also allow a reduction in side effects compared to systemic administration. There is evidence to support this technique.File Size: 1MB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761861/
Jan 29, 2016 · Intrathecal drug delivery systems can be used to manage refractory or persistent chronic nonmalignant (noncancer) pain. We investigated the benefits, harms, cost-effectiveness, and budget impact of these systems compared with current standards of care for adult patients with chronic pain owing to nonmalignant conditions.
https://www.medtronic.com/us-en/healthcare-professionals/therapies-procedures/neurological/targeted-drug-delivery.html
Targeted Drug Delivery Healthcare Professionals CONFIDENT PROGRAMMING ACCOMPLISHED Medtronic provides the latest in programming technology with the SynchroMed™ II Clinician Programmer featuring visuals, workflow guides, a vibrant backlit screen, and a wireless communicator to help simplify programming.
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