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https://www.sciencedaily.com/releases/2019/09/190925115117.htm
Sep 25, 2019 · The team tested the new drug delivery system by using UCLA-engineered fat cells to carry lipid-linked doxorubicin, a chemotherapy drug commonly used to …
https://newsroom.ucla.edu/releases/fat-cells-deliver-drug-suppresses-tumor-growth
Oct 03, 2019 · The researchers theorized that because fat cells are plentiful in the human body and can be easily isolated and purified, they could potentially serve as an efficient drug delivery system. However, tumor cells cause fat cells to release the fatty acids that support tumor growth.
https://news.northwestern.edu/stories/2019/07/trojan-horse-anticancer-drug-delivery-disguises-itself-as-fat/
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth.
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https://www.sciencedirect.com/science/article/pii/S1043276019302012
Advanced drug delivery systems have been developed over recent decades using an array of materials and chemical strategies. Biocompatible polymers are particularly attractive drug carrier matrices due to the versatility in polymer chemistry and ease of tailoring their physicochemical and biological properties .Polymeric carriers offer benefits in controlled and sustained delivery, extended ...Author: Di Huang, Meng Deng, Shihuan Kuang
https://www.cell.com/matter/fulltext/S2590-2385(19)30165-1
Adipocytes were engineered for local delivery of anticancer therapeutics, including fatty acid and small-molecule drug. The lipolysis triggered by tumor cells promoted the release of these anticancer therapeutics. In addition, the immunogenic tumor phenotype induced by anticancer fatty acid combined with tumor-responsive doxorubicin prodrug enhanced cancer therapy.Author: Di Wen, Di Wen, Jinqiang Wang, Jinqiang Wang, George Van Den Driessche, Qian Chen, Qian Chen, Yuqi Z...
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