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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
Aug 03, 2018 · Drug delivery technologies such as liquid, semi-solid or particulate formulations are important to deliver pharmaceutical compounds safely to their desired site of therapeutic activity . A highly critical point in drug delivery is the low availability of drugs in the central nervous system (CNS) due to the blood-brain barrier.Author: Stella Gänger, Katharina Schindowski
https://www.sciencedirect.com/science/article/pii/S0169409X11002900
Modern methods for delivery of drugs across the blood–brain barrier ... 5.2.1. Nanocarriers for brain drug delivery. Nanocarriers are an emerging class of drug delivery systems that can be easily tailored to delivery drugs to various parts of the body, including the brain. In the past decade, it has been attracting increasing attention for ...Author: Yan Chen, Lihong Liu
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Physical association of the drug to the nanoparticles was necessary for drug delivery to occur into the brain (Kreuter et al 2003). When nanoparticles with different surface characteristics were evaluated, neutral nanoparticles and low concentrations of anionic nanoparticles were found to have no effect on BBB integrity, whereas high ...Author: Wim H De Jong, Paul Ja Borm
https://www.nature.com/articles/s41467-019-13198-y
Nov 15, 2019 · We herein present novel materials and device technologies for drug delivery to brain tumors, i.e., a flexible, sticky, and biodegradable drug-loaded …Author: Jongha Lee, Hye Rim Cho, Gi Doo Cha, Hyunseon Seo, Hyunseon Seo, Seunghyun Lee, Chul Kee Park, Jin W...
http://jpet.aspetjournals.org/content/370/3/593
Sep 01, 2019 · Nose-to-Brain Mechanism of Delivery. For the purposes of drug delivery, the nasal cavity is divided into the respiratory area and the olfactory area, with the latter situated high up in the nares and the former closer to the nostrils (Sahin-Yilmaz and Naclerio, 2011).The nasal epithelium is well vascularized (Sahin-Yilmaz and Naclerio, 2011), and, within the olfactory area, olfactory neurons ...Author: Zian Wang, Guojun Xiong, Wai Chun Tsang, Andreas G. Schätzlein, Ijeoma F. Uchegbu
https://www.nature.com/articles/nrd.2015.21
Jan 22, 2016 · From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery William A. Banks 1 Nature Reviews Drug Discovery volume 15 , pages 275 – 292 ( 2016 ) Cite this articleAuthor: William A. Banks
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