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https://www.sciencedirect.com/science/article/pii/S0168365905007327
The experiments highlight the strength but also the limitations of using silk fibroin as a polymer for drug delivery. The motivation of this study was to combine the excellent biomaterial properties of silks—biocompatibility, mechanical integrity, and biodegradation—with drug delivery options.Author: S. Hofmann, C.T. Wong Po Foo, F. Rossetti, M. Textor, G. Vunjak-Novakovic, D.L. Kaplan, H.P. Merkle,...
https://www.ncbi.nlm.nih.gov/pubmed/16458987
Mar 10, 2006 · The pharmaceutical utility of silk fibroin (SF) materials for drug delivery was investigated. SF films were prepared from aqueous solutions of the fibroin protein polymer and crystallinity was induced and controlled by methanol treatment.Author: S. Hofmann, C.T. Wong Po Foo, F. Rossetti, M. Textor, G. Vunjak-Novakovic, D.L. Kaplan, H.P. Merkle,...
https://www.researchgate.net/publication/7315252_Silk_fibroin_as_an_organic_polymer_for_controlled_drug_delivery
Silk fibroin as an organic polymer for controlled drug delivery Article (PDF Available) in Journal of Controlled Release 111(1-2):219-27 · April 2006 with 234 Reads How we measure 'reads'
https://pure.tue.nl/ws/files/3744363/449224996622883.pdf
The present study relates to the understanding of silk fibroin processing and control of structure development (β-sheet con-tent as a reflection of degree of crystallinity) towards utility as a controlled release delivery matrix. The effect of the molecular weight of the compound to be delivered …
https://www.academia.edu/15154443/Silk_fibroin_as_an_organic_polymer_for_controlled_drug_delivery
Silk fibroin as an organic polymer for controlled drug delivery
https://www.sciencedirect.com/science/article/pii/S014296121000253X
Silk proteins are a promising material for drug delivery due to their aqueous processability, biocompatibility, and biodegradability. A simple aqueous preparation method for silk fibroin particles with controllable size, secondary structure and zeta potential is reported.Author: Andreas S. Lammel, Xiao Hu, Sang-Hyug Park, David L. Kaplan, Thomas R. Scheibel
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846964/
Silk proteins are a promising material for drug delivery due to their aqueous processability, biocompatibility, and biodegradability. A simple aqueous preparation method for silk fibroin particles with controllable size, secondary structure and zeta potential is reported.Author: Andreas S. Lammel, Xiao Hu, Sang-Hyug Park, David L. Kaplan, Thomas R. Scheibel
https://www.tandfonline.com/doi/abs/10.1517/17425247.2011.568936
Jan 09, 2015 · Silk fibroin represents a promising, naturally derived polymer for local, controlled, sustained drug release from fully degrading implants and the polymer can be processed into a broad array of material formats.Author: Eleanor M Pritchard, David L Kaplan
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