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https://link.springer.com/chapter/10.1007%2F3-540-45734-8_3
Feb 15, 2002 · Controlled drug delivery technology is concerned with the systematic release of a pharmaceutical agent to maintain a therapeutic level of the drug in the body for a sustained period of time. This may be achieved by incorporating the therapeutic agent into a degradable polymer vehicle, releasing the agent continuously as the matrix erodes.Author: Ulrica Edlund, A. C. Albertsson
https://www.researchgate.net/publication/225704244_Degradable_Polymer_Microspheres_for_Controlled_Drug_Delivery
Degradable Polymer Microspheres for Controlled Drug Delivery. Controlled drug delivery technology is concerned with the systematic release of a pharmaceutical agent to maintain a therapeutic level of the drug in the body for a sustained period of time.
https://www.sciencedirect.com/science/article/pii/S0378517304002492
Polymer microspheres can be employed to deliver medication in a rate-controlled and sometimes targeted manner. Medication is released from a microsphere by drug leaching from the polymer or by degradation of the polymer matrix.Author: S. Freiberg, X.X. Zhu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639710/
Polymer-based drug delivery systems provide a robust technology platform to enable sustained, spatio-temporally controlled drug release . Biodegradable polymers are of utmost interest, because they can be broken down and excreted or resorbed by the body without the necessity for removal interventions or surgical procedures ( 16 , 17 ).Author: Chunhui Jiang, Liangju Kuang, Madeline P. Merkel, Feng Yue, Mario Alberto Cano-Vega, Naagarajan Nara...
https://www.researchgate.net/publication/8956007_Microspheres_for_controlled_release_drug_delivery
Polymeric microspheres are ideal vehicles for many controlled delivery applications due to their ability to encapsulate a variety of drugs, biocompatibility, high bioavailability and sustained drug release characteristics. Research discussed in this review is focused on improving large-scale...
https://www.sciencedirect.com/science/article/pii/S0378517303001108
May 12, 2003 · The results indicated that the prodrug hydrophilicity had significant effects on the in vitro as well as in vivo drug release kinetics. The present study demonstrates the feasibility of using biodegradable polymeric microspheres for controlled delivery of NA prodrugs.Author: Fang I. Liu, J. H. Kuo, K. C. Sung, Oliver Y.P. Hu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792511/
Development and Characterization of Polymeric Microspheres for Controlled Release Protein Loaded Drug Delivery System S. Ravi , * K. K. Peh , Yusrida Darwis , B. Krishna Murthy , T. Raghu Raj Singh , and C. Mallikarjun
https://pubs.acs.org/doi/10.1021/acs.biomac.8b00266
The in vivo application of the paclitaxel-loaded PCL-OX microspheres provided a steady plasma drug concentration of 6–9 μg/mL over 28 days, similar to that of the PLGA microspheres. Both PCL and PLGA microspheres were completely cleared two months after in vivo implantation.Author: Seo Hee Chang, Hyun Jung Lee, Sohee Park, Yelin Kim, Byeongmoon Jeong
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
One such approach is using microspheres as carriers for drugs. The development of new delivery systems for the controlled release of drugs is one of the most interesting fields of research in pharmaceutical sciences. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy andFile Size: 1MB
https://link.springer.com/chapter/10.1007/978-1-4614-0881-9_8
Sep 27, 2011 · Drug loaded carriers from degradable polymers, namely, injectable microparticles, injectable in situ forming implants, and preformed implants, are established in the clinic for parenteral controlled drug delivery.Author: C. Wischke, S. P. Schwendeman
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