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https://www.researchgate.net/publication/225704244_Degradable_Polymer_Microspheres_for_Controlled_Drug_Delivery
This review is concerned with degradable polymers for use in controlled drug delivery with emphasis on the preparation, applications, biocompatibility, and stability of microspheres from ...
https://link.springer.com/chapter/10.1007%2F3-540-45734-8_3
Feb 15, 2002 · Controlled drug delivery technology is concerned with the systematic release of a pharmaceutical agent to maintain a therapeutic level of the drug in the body for a sustained period of time. This may be achieved by incorporating the therapeutic agent into a degradable polymer vehicle, releasing the agent continuously as the matrix erodes.Author: Ulrica Edlund, A. C. Albertsson
https://web.mit.edu/braatzgroup/mathematical_modeling_of_drug_delivery_from_autocatalytically_degradable_plga_microspheres_a_review.pdf
Controlled release drug delivery PLGA Autocatalysis Bulk degradation Degradable polymer PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. Au-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. Autocatalysis is known to have a complex role in ...Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://www.researchgate.net/publication/8956007_Microspheres_for_controlled_release_drug_delivery
Controlled release drug delivery employs drug-encapsulating devices from which therapeutic agents may be released at controlled rates for long periods of time, ranging from days to months.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859337/
The photoswitch compounds offer the possibility of a drug that can restore vision, but for this to be therapeutically viable, we need to have a delivery system that can provide local, sustained release. Our goal in this study was to optimize the loading and delivery of …Author: Rebecca Groynom, Erin Shoffstall, Larry S. Wu, Richard H. Kramer, Erin B. Lavik
https://pubs.acs.org/doi/10.1021/acs.biomac.8b00266
The in vivo application of the paclitaxel-loaded PCL-OX microspheres provided a steady plasma drug concentration of 6–9 μg/mL over 28 days, similar to that of the PLGA microspheres. Both PCL and PLGA microspheres were completely cleared two months after in vivo implantation.Author: Seo Hee Chang, Hyun Jung Lee, Sohee Park, Yelin Kim, Byeongmoon Jeong
https://www.sciencedirect.com/science/article/pii/S0168365912007353
Several mathematical models have been developed for the in vitro drug release kinetics from polymeric drug delivery devices (see Table 1, Table 2).This review aims to highlight mathematical models that mechanistically address the role of autocatalysis in the mass transport and chemical reaction phenomena of drug delivery from PLGA microspheres.Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://www.sciencedirect.com/science/article/abs/pii/S0168365912007353
Mathematical modeling of drug delivery from autocatalytically degradable PLGA microspheres — A review ... PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. ... of PLGA erosion and drug ...Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://www.mddionline.com/polymers-controlled-drug-delivery
Controlled drug delivery occurs when a polymer, whether natural or synthetic, is judiciously combined with a drug or other active agent in such a way that the active agent is released from the material in a predesigned manner.
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