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https://www.researchgate.net/publication/7471382_Cyclodextrins_in_drug_delivery_Review
trin derivatives for site-specific drug delivery and gene deliv- ery are being synthesised and tested in animals, as well as derivatives in which cyclodextrins are being used as pro-moie-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147107/
Applications of Cyclodextrins in Drug Delivery Systems. The multifunctional characteristics of CDs have enabled them to be used in almost every drug delivery system, be it oral drug delivery or transdermal drug delivery or ocular drug delivery.
https://www.ncbi.nlm.nih.gov/pubmed/16296758
In the pharmaceutical industry cyclodextrins have mainly been used as complexing agents to increase aqueous solubility of poorly soluble drugs, and to increase their bioavailability and stability. Studies in both humans and animals have shown that cyclodextrins can be used to improve drug delivery from almost any type of drug formulation.Author: Thorsteinn Loftsson, Pekka Jarho, Már Másson, Tomi Järvinen
https://link.springer.com/article/10.1208%2Fpt060243
Jun 01, 2005 · The purpose of this review is to discuss and summarize some of the interesting findings and applications of cyclodextrins (CDs) and their derivatives in different areas of drug delivery, particularly in protein and peptide drug delivery and gene delivery. The article highlights important CD applications in the design of various novel delivery systems like liposomes, microspheres, microcapsules ...Author: Rajeswari Challa, Alka Ahuja, Javed Ali, R. K. Khar
https://www.sciencedirect.com/science/article/pii/S1773224710500467
Cyclodextrins are one of the most versatile aids in pharmaceutical technology, being of interest for the formulation of a wide range of delivery devices from the most classical dosage forms to …Author: F.J. Otero-Espinar, J.J. Torres-Labandeira, C. Alvarez-Lorenzo, J. Blanco-Méndez
https://www.pharmaexcipients.com/cyclodextrin/cyclodextrins-drug-delivery/
This mini-review gives a summary on the basic complexation, drug delivery and biological properties of cyclodextrins and the cyclodextrin-based nano-scale drug delivery systems. Download the full MDPI publication here: Cyclodextrins in Drug Delivery Systems and their Effects on Biological Barriers
https://www.sciencedirect.com/topics/neuroscience/cyclodextrin
S. Narasimha Murthy, H.N. Shivakumar, in Handbook of Non-Invasive Drug Delivery Systems, 2010. 1.4.5 Complexation. Cyclodextrins are cyclic dextrose polymers that are known to enhance the aqueous solubility and stability of drugs on complex formation. The ring has a hydrophilic surface with a lipophilic core in which organic molecules of appropriate size can be held to form noncovalent ...
https://www.mdpi.com/2218-0532/87/4/33
On the other hand, they have numerous effects on cells or biological barriers. In this review the most important properties of cyclodextrins and cyclodextrin-based drug delivery systems are summarized with special focus on their biological activity.Author: Ádám Haimhoffer, Ágnes Rusznyák, Katalin Réti-Nagy, Gábor Vasvári, Judit Váradi, Miklós Vecsernyés, ...
https://link.springer.com/article/10.1007/s13346-020-00724-5
Feb 19, 2020 · Gene therapy is a powerful tool against genetic disorders and cancer, targeting the source of the disease rather than just treating the symptoms. While much of the initial success of gene delivery relied on viral vectors, non-viral vectors are emerging as promising gene delivery systems for efficacious treatment with decreased toxicity concerns.Author: Rebecca M. Haley, Riccardo Gottardi, Riccardo Gottardi, Robert Langer, Michael J. Mitchell
https://www.tandfonline.com/doi/abs/10.1517/17425247.2.1.335
Aug 12, 2015 · In the pharmaceutical industry cyclodextrins have mainly been used as complexing agents to increase aqueous solubility of poorly soluble drugs, and to increase their bioavailability and stability. Studies in both humans and animals have shown that cyclodextrins can be used to improve drug delivery from almost any type of drug formulation.Author: Thorsteinn Loftsson, Pekka Jarho, Már Másson, Tomi Järvinen
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