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http://www.vetmed.vt.edu/clinical-trials/canine-glioma/convection-enhanced-delivery.asp
Convection Enhanced Delivery (CED) is a therapeutic strategy that was developed to facilitate targeted delivery of pharmaceuticals to the brain. The CED procedure involves a minimally invasive surgical exposure of the brain, followed by placement of small diameter catheters directly into the brain tumor. Subsequently, infusion of therapeutics into the tumor occurs over several hours to saturate the target …
https://www.ott.nih.gov/technology/e-173-1992
Convection-Enhanced Drug Delivery System. This application describes an apparatus and method of convection-enhanced delivery of drugs into the brain and other solid tissue structures.
https://www.frontiersin.org/articles/10.3389/fonc.2019.00966/full
Convection enhanced delivery (CED) is a method used to increase transport of therapeutics in and around brain tumors. CED works through locally applying a pressure differential to drive fluid flow throughout the tumor, such that convective forces dominate over diffusive transport.Author: Caleb A. Stine, Jennifer M. Munson
https://link.springer.com/article/10.1007/s13311-017-0520-4
Mar 15, 2017 · Convection-enhanced delivery (CED) is a promising technique that generates a pressure gradient at the tip of an infusion catheter to deliver therapeutics directly through the interstitial spaces of the central nervous system.Author: A. M. Mehta, A. M. Sonabend, J. N. Bruce
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327456/
Convection-enhanced delivery (CED) is a technique designed to deliver drugs directly into the brain or tumors. Its ability to bypass the blood-brain barrier (BBB), one of the major hurdles in delivering drugs to the brain, has made it a promising drug delivery method for the treatment of primary brain tumors.Author: Zhiping Zhou, Ranjodh Singh, Mark M. Souweidane
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