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http://www.vetmed.vt.edu/clinical-trials/canine-glioma/convection-enhanced-delivery.asp
Convection Enhanced Delivery (CED) is a therapeutic strategy that was developed to facilitate targeted delivery of pharmaceuticals to the brain. The CED procedure involves a minimally invasive surgical exposure of the brain, followed by placement of small diameter catheters directly into the brain tumor .
https://www.frontiersin.org/articles/10.3389/fonc.2019.00966/full
Convection enhanced delivery (CED) is a method used to increase transport of therapeutics in and around brain tumors. CED works through locally applying a pressure differential to drive fluid flow throughout the tumor, such that convective forces dominate over diffusive transport.Author: Caleb A. Stine, Jennifer M. Munson
https://braintumorcenter.ucsf.edu/treatment/experimental-diagnostics-therapies/convection-enhanced-delivery
To address this problem, researchers at UCSF and elsewhere have been developing a procedure called convection-enhanced delivery (CED). CED is an experimental technique for directly infusing drugs into a brain tumor. This increases drug efficacy while reducing side effects to …
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30322-X/fulltext
It is possible that convection-enhanced delivery-based therapy, if used early enough in the disease course, could impart a survival benefit with local control. If regional control can be demonstrated with convection-enhanced delivery-based therapy, combinatorial approaches would be logical extensions of this strategy for future studies.Author: Mark M Souweidane, Mark M Souweidane, Kim Kramer, Kim Kramer, Neeta Pandit-Taskar, Neeta Pandit-Task...
https://clinicaltrials.gov/ct2/show/NCT03566199
Jun 25, 2018 · To determine the clinical efficacy of repeated administration of MTX110 given by intratumoral convection-enhanced delivery (CED) in children with newly diagnosed DIPG in the confines of a phase I and early efficacy study. OUTLINE: This is a phase I, dose-escalation study followed by a phase II study.
https://link.springer.com/content/pdf/10.1016%2Fj.nurt.2009.01.017.pdf
Convection-Enhanced Delivery in the Treatment of Epilepsy Michael A. Rogawski Department of Neurology, School of Medicine, University of California, Davis, Sacramento, California 95817 Summary: Convection-enhanced delivery (CED) is a novel drug-delivery …Author: Michael A. Rogawski
https://clinicaltrials.gov/ct2/show/NCT02858895
Aug 08, 2016 · Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
https://clinicaltrials.gov/ct2/show/NCT02278510
Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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